Clinical features and literature review of Cogan’s syndrome with bilateral internal carotid artery occlusion

Abstract

Cogan’s syndrome is rare. The purpose of this article is to describe a Cogan’s syndrome case characterized by bilateral internal carotid artery occlusion and to review the literature. Treatment remedies: we showed a patient with vertigo, nausea and retching, blurred vision, unclear speech. And the whole cerebral angiogram of the patient showed bilateral internal carotid artery occlusion without obvious neurological deficit. After differential diagnosis, compared with classic Cogan’s syndrome, granulomatous polyvasculitis (GPA), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), the patient was considered as Cogan’s syndrome. Post treatment evaluating: the patient did not significantly improve vertigo after vascular bypass therapy. Conclusions: Cogan’s syndrome may cause severe vascular occlusion. The patient had no clinical symptoms; and the chronic occlusion caused by vascular inflammation may be the reason, so that there was enough time for compensation.

Keywords

Cogan’s syndrome / granulomatous polyvasculitis (GPA) / digital subtraction angiography (DSA) / compensation / artery occlusion