Synthesis of Fluorene Derivatives Via TfOH-catalyzed Intramolecular Friedel-Crafts Alkylation Reactions

Abstract

We devoloped an efficient and simple method to synthesize fluorene derivatives via intramolecular Friedel-Crafts alkylation of chalcones. The transform is catalyzed by TfOH in CH₃NO₂ at 80 °C and the yield is up to 99%.

Keywords

fluorene / intramolecular alkylation / TfOH

References

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