Preparation of elemental tellurium nanoparticles — sucrose sol and its antioxidant activity in vitro

Abstract

The elemental tellurium nanoparticles (TeNPs) — sucrose sol was prepared by the reaction of sodium tellurite with ascorbic acid in sucrose aqueous solution. The results indicated that TeNPs were dispersion excellent in the TeNPs — sucrose sol and the morphology of TeNPs was needle-like with about 70 nm in width and 500 nm in length. The antioxidant activity of the TeNPs — sucrose sol in vitro was estimated by pyrogallol autoxidation method, Fenton method and oxygen radical absorbance capacity (ORAC) assay. The results showed that a certain amount of TeNPs — sucrose sol could effectively scavenge superoxide anion free radical and hydroxyl free radical with scavenging rates of 73 % and 57 %, respectively. ORAC assay was used to measure the total antioxidant capacity of TeNPs — sucrose sol. The order of ORAC values was 2.25 μmol·L⁻¹ TeNPs — 0.025 % sucrose sol > 0.025 % sucrose > 2.25 μmol·L⁻¹ Na₂TeO₃ > 1.63 μmol·L⁻¹ ascorbic acid. The results suggested that the TeNPs — sucrose sol had the excellent antioxidant activity and TeNPs were the dominating contributors to antioxidant capacity of the TeNPs — sucrose sol.

Keywords

tellurium nanoparticles — sucrose sol / superoxide anion free radical / hydroxyl free radical; oxygen radical absorbance capacity (ORAC)

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