Contraceptive efficacy and local effects of bioceramic IUD in rat

Wang Yan , Zhang Yuanzhen , Yan Yuhua , Chen Weimin , Liu Wenhui , Zu Meiping

Journal of Wuhan University of Technology Materials Science Edition ›› 2006, Vol. 21 ›› Issue (4) : 99 -101.

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Journal of Wuhan University of Technology Materials Science Edition ›› 2006, Vol. 21 ›› Issue (4) : 99 -101. DOI: 10.1007/BF02841215
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Contraceptive efficacy and local effects of bioceramic IUD in rat

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Abstract

The contraceptive efficacy and local effects of bioceramic IUD in rat were studied. The experiment was divided into four groups: bioceramic IUD group; stainless steel IUD group; operation control group; normal control group. All IUD samples were put into uterus of rats. The experimental results show that the alumina bioceramic has a strong contraceptive effect for those rats. In bioceramic IUD group the endometrial inflammation reaction was as mild as that in stainless IUD group during the early days (30 days) and gradually abated with time during the late days (60 days). The experiments show that the alumina bioceramic has a good biocompatibility and contraceptive effects and hint at the alumina bioceramic IUD may become a more safety reproduction family planning IUD.

Keywords

alumina bioceramic / IUD / contraception

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Wang Yan, Zhang Yuanzhen, Yan Yuhua, Chen Weimin, Liu Wenhui, Zu Meiping. Contraceptive efficacy and local effects of bioceramic IUD in rat. Journal of Wuhan University of Technology Materials Science Edition, 2006, 21(4): 99-101 DOI:10.1007/BF02841215

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References

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Peng Dengren Zhao Yongquan. Study of Effect of the Contraceptive LNGR-IUD on Endometrium and Main Organs in Rat [J]. Peproduction & Contraception, 1991, 11(3): 43-45.

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Dingshou Zhu, Xingcui Wang, Xiaolan Liu. The Contraceptive Efficacy and Local Effects of Different Tape of IUD inserted Female Rats[J]. The Journal of Beijing Second Medical College, 1981, 3: 214-217.

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Shipu Li, Xiaoming Chen. Bioceramics, 1989 Wuhan: Wuhan University of Technology Press. 10-24.

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Zilan Lu. The Theory and Practice of Family Planning, 1989 Shaoguan: Science and Technology Press. 204-206.

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