Quantitative similarity assessment of non-linear chemical fingerprint of traditional Chinese medicine by similarity system theory

Abstract

The similarities of the non-linear chemical (NLC) fingerprints of Radix Glycyrrhizaes from four producing areas and eight other traditional Chinese medicines (TCMs) were calculated, using a systemic similarity calculation method proposed and three other main calculation ones (Euclidean distance, correlation coefficient and included angle cosine). All of the correlation coefficient similarities of different TCMs are higher than 0.952, and the included angle cosines are all higher than 0.962. So, both the correlation coefficient and included angle cosine similarities are unable to be used as the criteria for quantitatively evaluating the similarities of NLC fingerprints of TCMs. Although all of the Euclidean distance similarities of Berry Liquorices from four producing areas are less than 73, those of the other eight TCMs are all more than 180. The Euclidean distance cannot reflect the relative magnitudes of the feature differences in the NLC fingerprints very correctly. The systemic similarity method is the best among the four ones. All of the systemic similarities of Berry Liquorices from the four producing areas are higher than 0.962, while those of the other eight TCMs are all lower than 0.805, and the systemic similarity can reflect the differences between samples most faithfully, and can be used as a quantitative one evaluating the similarities of NLC fingerprints of TCMs, by which TCM could be distinguished and evaluated quickly, simply and exactly.

Keywords

nonlinear chemistry fingerprint / systemic similarity / traditional Chinese medicine

References

[1] XueT.-h., RoyR.. Studying traditional Chinese medicine [J]. Science, 2003, 300(5620): 740-741

[2] ChenL., TangY. P., ChenM. J., DengH. S., YanX. P., WuD. K.. Chemical correlation between Gegen Qinlian dispensing granule and its four raw herbs by LC fingerprint [J]. Phytomedicine, 2010, 17: 100-107

[3] XieP. S., ChenS. B., LiangY. Z., WangX. H., TianR. T., UptonR.. Chromatographic fingerprint analysis—A rational approach for quality assessment of traditional Chinese herbal medicine [J]. Journal of Chromatography A, 2006, 1112: 171-180

[4] GuoF.-q., LiangY.-z., HuangL.-f., XuC.-Jian.. Fingerprint analysis of the volatile chemical constituents in artemisia capillaris herba via gas chromatography-mass spectrum [J]. Chemical Jounal of Chinese Universties, 2005, 26(11): 2027-2030

[5] GuM., ZhangS. F., SuZ. G., ChenY., FanO. Y.. Fingerprinting of Salvia Miltiorrhiza Bunge by non-aqueous capillary electrophoresis compared with high-speed counter-current chromatography [J]. Journal of Chromatography A, 2004, 1057: 133-140

[6] ZhaX. Q., LuoJ. P., WeiP.. Identification and classification of Dendrobium candidum species by fingerprint technology with capillary electrophoresis [J]. South African Journal of Botany, 2009, 75: 276-282

[7] LuJ., XiangB.-r., LiuH., XiangS.-y., XieS.-f., DengH.-shan.. Application of two-dimensional near-infrared correlation spectroscopy to the discrimination of Chinese herbal medicine of different geographic regions [J]. Spectrochimica Acta Part A, 2008, 69: 580-586

[8] FieldR. T., KörösE., NoyesR. M.. Oscillation in chemical system. II: Thorough analysis of temporal oscillation in the bromate-cerium-malonic acid system [J]. Journal of the American Chemical Society, 1972, 94(25): 8649-8664

[9] FieldR. J., SchneiderF. W.. Oscillating chemical reaction and nonlinear dynamics [J]. Journal of Chemical Education, 1989, 66: 195-204

[10] TaylorA. F.. Mechanism and phenomenology of an oscillating chemical reaction [J]. Chaos, 2002, 27(4): 247-325

[11] PrjmanJ. A., EpsteinI. R., McmanusT. J.. Convective effects on chemical waves. 2: Simple convection in the Iodate-Arsenous acid system [J]. J Phys Chem Journal of Physical Chemistry, 1991, 95: 1299-1306

[12] ZhangY.-z., AnC.-j., DingZ.-z., ZhengD., XieYing.. Kinetic study on HCHO-lactic acid-actone-BrO₃⁻-Mn²⁺-H₂SO₄ chemical oscillation reaction [J]. Journal of Analytical Science, 2004, 20(5): 468-470

[13] GanN. Q., CaiR. X., LinZ. X.. Determination of ascorbic acid based on a peroxidase oscillator reaction [J]. Anal Chim Acta, 2002, 466(2): 257-260

[14] WangJ., YangS. T., CaiR. X., LinZ. X., LiuZ. H.. A new method for determination of uric acid by the lactic acid-acetone-BrO₃-Mn²⁺-H₂SO₄ oscillating reaction using the analyte pulse perturbation technique [J]. Talanta, 2005, 65(3): 799-805

[15] LiZ.-x., YuanC.-l., NieFei.. Application of chemical oscillation technique in herb’s study [J]. Chinese Basic Science, 2004, 6(2): 27-29

[16] ZhangM.-min.. Application of chemical oscillation in study on Chinese materia medica [J]. Chin Tradit Herb Drugs, 2006, 37(7): 961-96

[17] WANG Yuan, LI Zong-xiao. The oscillating fingerprints of ten kinds of herbal medicines [J]. Chem World, 2007, (8): 464–467. (in Chinese)

[18] ZhangT.-m., LiangY.-z., YuanB., DingF., ZhangY.-e., WeiM.-q., ChenXu.. Determining method and conditional factors of electrochemical fingerprint of Chinese traditional medicine [J]. Chinese Science Bulletin, 2007, 52(16): 2202-2215

[19] ZhangT.-m., LiangY.-z., YuanB., DingF., ZhangY.-p., ChenW.-yan.. Principle, traits and functions of electrochemical fingerprint for distinguishing and evaluating Chinese traditional medicine [J]. Chinese Science Bulletin, 2007, 52(20): 2753-2765

[20] ZhouM.-li.. Principles and pracitice of similarity system theory [J]. International Journal of General Systems, 1994, 23(1): 39-48

[21] ZhouM.-li.. Principles of similarity formation between similar systems [J]. International Journal of General Systems, 1999, 27(6): 495-504

[22] BeniniO., CervellatiR., FettoP.. The BZ reaction: Experimental and model studies in the physical chemistry laboratory [J]. Journal of Chemical Education, 1996, 73(9): 865-868

[23] FieldR. J., ShneiderF. W.. Oscillating chemical reaction and nonlinear dynamics [J]. Journal of Chemical Education, 1989, 66(2): 195-204

[24] ZouH.-b., YangG.-s., DuA.-q., YuanJ. R., QinZ. R.. Combinational numeral fingerprint spectra of Glycyrrhiza and analysis of common peak ratio invariableness in HPLC [J]. Biomedical Chromatography, 2006, 20(6): 642-655

[25] YeH., ShenS., ZhangX.-min.. Study on the quality control of flos chrysanthemi indici by HPLC chromatographic fingerprint with eudidean distance [J]. World Sci-Tech R&D, 2006, 28(2): 72-74

[26] YangB.-j., ChenJ.-h., LeeF. S. C.. GC-MS fingerprints for discrimination of Ligusticum chuanxiong from Angelica [J]. Journal of Separation Science, 2008, 31(18): 3231-3237

[27] JinY., LiangT., FuQ., XiaoY.-s., FengJ.-t., KeY.-x., LiangX.-miao.. Fingerprint analysis of Ligusticum chuanxiong using hydrophilic interaction chromatography and reversed-phase liquid chromatography [J]. Journal of Chromatography A, 2009, 1216(11): 2136-2141

[28] XieG.-x., ZhaoA.-h., LiPeng.. Fingerprint analysis of Rhizoma chuanxiong by pressurized capillary electrochromatography and high-performance liquid chromatography [J]. Biomedical Chromatography, 2007, 21(8): 867-875

[29] PangT.-t., DuL.-ming.. Common and variant peak ratios in ir fingerprint of ilex kudingcha with duel-index sequence analysis [J]. Spectroscopy and Spectral Analysis, 2007, 27(3): 486-489