Organic-inorganic bio-composite as bone substitute

Abstract

Organic-inorganic composite biomaterial (HA-TCP-BMP) used as bone substitutes and the fabrication process are described in this paper. The quantitative calculation ofβ-whithokite presented in sintered material is about 14%–18% and the ratio of Ca/P is about 1.61. The influences of the composition and structure on the bone forming properties and biologic effects are discussed. Meanwhile, the results of clinical application of the composite materials are viewed. The research results show that the composite material can be completely degradated in controlle time and at the operation site new formed bone can fully replace the implanted material.

Keywords

biomaterial / biologic effects / clinic application