Impact of anthocyanin fromMalva sylvestris on plasma lipids and free radical

Abstract

The effects of anthocyanin fromMalva sylvestris on plasma lipids and free radical were investigated by Reagent Kit method and in vitro assay. High fat model was set up with albino rats that were fed with different dosages of anthocyanin fromMalva sylvestris (0.03 g·d⁻¹, 0.04 g·d⁻¹ and 0.05 g·d⁻¹). The results showed that the total cholesterol was decreased by 19.7% at an anthocyanin of 0.04 g·d⁻¹ and triglyceride was decreased by 34.4% at an anthocyanin of 0.05 g·d⁻¹. In vitro assay, some indexes of anthocyanin were measured including the capability of scavenging free radical, reducing force and the capability of anti-lipid peroxidation by orthophenanthroline Fe⁺² oxidation-reduction method. The results indicated that the clearance rate of free radical reached to 43.46% when the content of anthocyanin was 0.20 mg·mL⁻¹ and the inhibition ratio of lipid peroxidation reached 18.82% when the content was 0.5 mg·mL⁻¹. Therefore anthocyanin is a kind of natural and effective free radical remover and antioxidant and can prevent from the formation of the thrombus and reduced the emergence of the cardiovascular disease.

Keywords

Anthocyanin / Plasma lipids / Free radical / Q493 / A