Epidemiology of constipation in adults: Why estimates of prevalence differ

Barry L. Werth

Journal of Epidemiological Research ›› 2019, Vol. 5 ›› Issue (1) : 37 -49.

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Journal of Epidemiological Research ›› 2019, Vol. 5 ›› Issue (1) :37 -49. DOI: 10.5430/jer.v5n1p37
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Epidemiology of constipation in adults: Why estimates of prevalence differ
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Abstract

This review of over 80 articles published in the last 30 years shows that estimates of the prevalence of chronic constipation in community-dwelling adults varied widely from 2.4% to 39.6% in general adult populations and from 4% to 25.8% in older adult populations. Estimates of the prevalence of any constipation (including both chronic and sporadic constipation) also varied widely from 2.6% to 31.0% in general adult populations and from 4.4% to 44.5% in older adult populations. Apart from any country or regional differences, this wide range of estimated prevalence may be attributed to different definitions used for both chronic and any constipation as well as different data collection methods and sampling differences. Sampling issues include sample size, representativeness and age range of populations sampled. Further research is required to examine the impact of different definitions on prevalence estimates to help determine the best definitions for use in future epidemiological studies. If standard definitions can be universally agreed and used, along with appropriate sampling and data collection methods, more precise estimates of constipation prevalence should be attained. This would allow more meaningful comparisons between countries and may also provide the ability to pool results.

Keywords

Prevalence / Measurement / Adults / Constipation / Epidemiology

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Barry L. Werth. Epidemiology of constipation in adults: Why estimates of prevalence differ. Journal of Epidemiological Research, 2019, 5(1): 37-49 DOI:10.5430/jer.v5n1p37

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References

[1]

Talley NJ. Definitions, epidemiology, and impact of chronic constipation. Rev Gastroenterol Disord. 2004; 4(Suppl.2): S3-S10. PMid:15184814.

[2]

Dennison C, Prasad M, Lloyd A, et al. The health-related quality of life and economic burden of constipation. Pharmacoeconomics. 2005; 23(5): 461-76. PMid:15896098. https://doi.org/10.2165/00019053-200523050-00006

[3]

Mugie SM, Benninga MA, Di Lorenzo C. Epidemiology of constipation in children and adults: a systematic review. Best Pract Res Clin Gastroenterol. 2011; 25(1): 3-18. PMid:21382575. https://doi.org/10.1016/j.bpg.2010.12.010

[4]

Suares NC, Ford AC. Prevalence of, and risk factors for, chronic idiopathic constipation in the community: systematic review and meta-analysis. Am J Gastroenterol. 2011; 106(9): 1582-91. PMid:21606976. https://doi.org/10.1038/ajg.2011.164

[5]

Drossman DA. Functional gastrointestinal disorders: History, pathophysiology, clinical features, and Rome IV. Gastroenterology. 2016; 150(6): 1262-79. PMid:27144617. https://doi.org/10.1053/j.gastro.2016.02.032

[6]

Singh S, Bajorek B. Pharmacotherapy in the ageing patient: The impact of age per se. Ageing Res Rev. 2015; Part B. 24: 99-110.

[7]

Grant MJ, Booth A. A typology of reviews: An analysis of 14 review types and associated methodologies. Health Info Libr J. 2009; 26(2): 91-108. PMid:19490148. https://doi.org/10.1111/j.1471-1842.2009.00848.x

[8]

Schmidt FM, Santos VL. Prevalence of constipation in the general adult population: an integrative review. J Wound Ostomy Continence Nurs. 2014; 41(1): 70-6. PMid:24378694. https://doi.org/10.1097/01.WON.0000438019.21229.b7

[9]

Higgins PD, Johanson JF. Epidemiology of constipation in North America: a systematic review. Am J Gastroenterol. 2004; 99(4): 750-9. PMid:15089911. https://doi.org/10.1111/j.1572-0241.2004.04114.x

[10]

Hammond EC. Some Preliminary Findings on Physical Complaints from a Prospective Study of 1,064,004 Men and Women. Am J Public Health Nations Health. 1964; 54: 11-23. PMid:14117648. https://doi.org/10.2105/AJPH.54.1.11

[11]

Talley NJ, Zinsmeister AR, Van Dyke C, Melton LJ, 3rd. Epidemiology of colonic symptoms and the irritable bowel syndrome. Gastroenterology. 1991; 101(4): 927-34. https://doi.org/10.1016/0016-5085(91)90717-Y

[12]

Talley NJ, Weaver AL, Zinsmeister AR, Melton LJ, 3rd. Functional constipation and outlet delay: a population-based study. Gastroenterology. 1993; 105(3): 781-90. https://doi.org/10.1016/0016-5085(93)90896-K

[13]

Drossman DA, Li Z, Andruzzi E, et al. U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig Dis Sci. 1993; 38(9): 1569-80. PMid:8359066. https://doi.org/10.1007/BF01303162

[14]

Pare P, Ferrazzi S, Thompson WG, et al. An epidemiological survey of constipation in Canada: Definitions, rates, demographics, and predictors of health care seeking. Am J Gastroenterol. 2001; 96(11): 3130-7. PMid:11721760. https://doi.org/10.1111/j.1572-0241.2001.05259.x

[15]

Sandler RS, Jordan MC, Shelton BJ. Demographic and dietary determinants of constipation in the US population. Am J Public Health. 1990; 80(2): 185-9. PMid:2297063. https://doi.org/10.2105/AJPH.80.2.185

[16]

Everhart JE, Go VL, Johannes RS, et al. A longitudinal survey of self-reported bowel habits in the United States. Dig Dis Sci. 1989; 34(8): 1153-62. PMid:2787735. https://doi.org/10.1007/BF01537261

[17]

Harari D, Gurwitz JH, Avorn J, et al. Bowel habit in relation to age and gender. Findings from the National Health Interview Survey and clinical implications. Arch Intern Med. 1996; 156(3): 315-20. PMid:8572842. https://doi.org/10.1001/archinte.1996.00440030117014

[18]

Johanson JF, Sonnenberg A, Koch TR. Clinical epidemiology of chronic constipation. J Clin Gastroenterol. 1989; 11(5): 525-36. PMid:2551954. https://doi.org/10.1097/00004836-198910000-00008

[19]

Stewart WF, Liberman JN, Sandler RS, et al. Epidemiology of constipation (EPOC) study in the United States: relation of clinical subtypes to sociodemographic features. Am J Gastroenterol. 1999; 94(12): 3530-40. PMid:10606315. https://doi.org/10.1111/j.1572-0241.1999.01642.x

[20]

Chang JY, Locke GR, Schleck CD, et al. Risk factors for chronic constipation and a possible role of analgesics. Neurogastroenterol Motil. 2007; 19(11): 905-11. PMid:17988275. https://doi.org/10.1111/j.1365-2982.2007.00974.x

[21]

Choung RS, Locke GR, Zinsmeister AR, et al. Alternating bowel pattern: what do people mean? Aliment Pharmacol Ther. 2006; 23(12): 1749-55. PMid:16817919. https://doi.org/10.1111/j.1365-2036.2006.02953.x

[22]

Tuteja AK, Talley NJ, Joos SK, et al. Is constipation associated with decreased physical activity in normally active subjects? Am J Gastroenterol. 2005; 100(1): 124-9. PMid:15654791. https://doi.org/10.1111/j.1572-0241.2005.40516.x

[23]

Johanson JF, Kralstein J. Chronic constipation: a survey of the patient perspective. Aliment Pharmacol Ther. 2007; 25(5): 599-608. PMid:17305761. https://doi.org/10.1111/j.1365-2036.2006.03238.x

[24]

Wald A, Scarpignato C, Mueller-Lissner S, et al. A multinational survey of prevalence and patterns of laxative use among adults with self-defined constipation. Aliment Pharmacol Ther. 2008; 28(7): 917-30. https://doi.org/10.1111/j.1365-2036.2008.03806.x

[25]

Choung RS, Rey E, Locke GR, et al. Chronic constipation and comorbidities: A prospective population-based nested case-control study. United European Gastroenterol J. 2016; 4(1): 142-51. PMid:26966534. https://doi.org/10.1177/2050640614558476

[26]

Markland AD, Palsson O, Goode PS, et al. Association of low dietary intake of fiber and liquids with constipation: evidence from the National Health and Nutrition Examination Survey. Am J Gastroenterol. 2013; 108(5): 796-803. PMid:23567352. https://doi.org/10.1038/ajg.2013.73

[27]

Heidelbaugh JJ, Stelwagon M, Miller SA, et al. The spectrum of constipation-predominant irritable bowel syndrome and chronic idiopathic constipation: US survey assessing symptoms, care seeking, and disease burden. Am J Gastroenterol. 2015; 110(4): 580-7. PMid:25781368. https://doi.org/10.1038/ajg.2015.67

[28]

Palsson OS, Whitehead WE, Van Tilburg MAL, et al. Development and validation of the Rome IV diagnostic questionnaire for adults. Gastroenterology. 2016; 150(6): 1481-91. PMid:27144634 https://doi.org/10.1053/j.gastro.2016.02.014

[29]

Halder SLS, Locke GR, Schleck CD, et al. Natural history of functional gastrointestinal disorders: a 12-year longitudinal population-based study. Gastroenterology. 2007; 133(3): 799-807. PMid:17678917 https://doi.org/10.1053/j.gastro.2007.06.010

[30]

Choung RS, Locke GR, Rey E, et al. Factors associated with persistent and nonpersistent chronic constipation, over 20 years. Clin Gastroenterol Hepatol. 2012; 10(5): 494-500. PMid:22289877. https://doi.org/10.1016/j.cgh.2011.12.041

[31]

Peppas G, Alexiou VG, Mourtzoukou E, et al. Epidemiology of constipation in Europe and Oceania: a systematic review. BMC Gastroenterol. 2008; 8(5). https://doi.org/10.1186/1471-230X-8-5

[32]

Walter S, Hallbook O, Gotthard R, et al. A population-based study on bowel habits in a Swedish community: prevalence of faecal incontinence and constipation. Scand J Gastroenterol. 2002; 37(8): 911-6. PMid:12229965. https://doi.org/10.1080/003655202760230865

[33]

Haug TT, Mykletun A, Dahl AA. Are anxiety and depression related to gastrointestinal symptoms in the general population? Scand J Gastroenterol. 2002; 37(3): 294-8. PMid:11916191. https://doi.org/10.1080/003655202317284192

[34]

Siproudhis L, Pigot F, Godeberge P, et al. Defecation disorders: a French population survey. Dis Colon Rectum. 2006; 49(2): 219-27. PMid:16362804. https://doi.org/10.1007/s10350-005-0249-8

[35]

Garrigues V, Galvez C, Ortiz V, et al. Prevalence of constipation: agreement among several criteria and evaluation of the diagnostic accuracy of qualifying symptoms and self-reported definition in a population-based survey in Spain. Am J Epidemiol. 2004; 159(5): 520-6. PMid:14977649. https://doi.org/10.1093/aje/kwh072

[36]

Bassotti G, Bellini M, Pucciani F, et al. An extended assessment of bowel habits in a general population. World J Gastroenterol. 2004; 10(5): 713-6. PMid:14991944. https://doi.org/10.3748/wjg.v10.i5.713

[37]

Fosnes GS, Lydersen S, Farup PG. Constipation and diarrhoea - common adverse drug reactions? A cross sectional study in the general population. BMC Clin Pharmacol. 2011; 11. https://doi.org/10.1186/1472-6904-11-2

[38]

Eikendal T, Laheij RJF, et al. Gastrointestinal symptoms are still common in a general Western population. Neth J Med. 2008; 66(1): 18-22. PMid:18219063.

[39]

Meinds RJ, van Meegdenburg MM, Trzpis M, et al. On the prevalence of constipation and fecal incontinence, and their co-occurrence, in the Netherlands. Int J Colorectal Dis. 2017; 32(4): 475-83. PMid:27913883. https://doi.org/10.1007/s00384-016-2722-3

[40]

Enck P, Leinert J, Smid M, et al. Prevalence of constipation in the German population-a representative survey (GECCO). United European Gastroenterol J. 2016; 4(3): 429-37. PMid:27403310. https://doi.org/10.1177/2050640615603009

[41]

Papatheodoridis GV, Vlachogiannakos J, Karaitianos I, et al. A Greek survey of community prevalence and characteristics of constipation. Eur J Gastroenterol Hepatol. 2010; 22(3): 354-60. PMid:19474747. https://doi.org/10.1097/MEG.0b013e32832bfdf0

[42]

Pamuk ON, Pamuk GE, Celik AF. Revalidation of description of constipation in terms of recall bias and visual scale analog questionnaire. J Gastroenterol Hepatol. 2003; 18(12): 1417-22. PMid:14675272. https://doi.org/10.1046/j.1440-1746.2003.03155.x

[43]

Ebling B, Gulic S, Jurcic D, et al. Demographic, anthropometric and socioeconomic characteristics of functional constipation in Eastern Croatia. Coll Antropol. 2014; 38(2): 539-46. PMid:25144985.

[44]

Esteban Y, Pena M, Garcia RJ, et al. Impact of the most frequent chronic health conditions on the quality of life among people aged > 15 years in Madrid. Eur J Public Health. 2010; 20(1): 78-84. PMid:19587225. https://doi.org/10.1093/eurpub/ckp098

[45]

Rey E, Balboa A, Mearin F. Chronic constipation, irritable bowel syndrome with constipation and constipation with pain/discomfort: similarities and differences. Am J Gastroenterol. 2014; 109(6): 876-84. PMid:24589666. https://doi.org/10.1038/ajg.2014.18

[46]

Tamura A, Tomita T, Oshima T, et al. Prevalence and self-recognition of chronic constipation: Results of an internet survey. J Neurogastroenterol Motil. 2016; 22(4): 677-85. PMid:27426278. https://doi.org/10.5056/jnm15187

[47]

Chen LY, Ho KY, Phua KH. Normal bowel habits and prevalence of functional bowel disorders in Singaporean adults-findings from a community based study in Bishan. Singapore Med J. 2000; 41(6): 255-8. PMid:11109339.

[48]

Ho KY, Kang JY, Seow A. Prevalence of gastrointestinal symptoms in a multiracial Asian population, with particular reference to reflux-type symptoms. Am J Gastroenterol. 1998; 93(10): 1816-22. PMid:9772037. https://doi.org/10.1111/j.1572-0241.1998.00526.x

[49]

Chang FY, Chen PH, Wu TC, et al. Prevalence of functional gastrointestinal disorders in Taiwan: questionnaire-based survey for adults based on the Rome III criteria. Asia Pacific J Clin Nutr. 2012; 21(4): 594-600. PMid:23017318.

[50]

Lu CL, Chang FY, Chen CY, et al. Significance of Rome II-defined functional constipation in Taiwan and comparison with constipation-predominant irritable bowel syndrome. Aliment Pharmacol Ther. 2006; 24(2): 429-38. PMid:16842471. https://doi.org/10.1111/j.1365-2036.2006.02949.x

[51]

Jun DW, Park HY, Lee OY, et al. A population-based study on bowel habits in a Korean community: prevalence of functional constipation and self-reported constipation. Dig Dis Sci. 2006; 51(8): 1471-7. PMid:16832618. https://doi.org/10.1007/s10620-006-9087-3

[52]

Jeong JJ, Choi MG, Cho YS, et al. Chronic gastrointestinal symptoms and quality of life in the Korean population. World J Gastroenterol. 2008; 14(41): 6388-94. PMid:19009657. https://doi.org/10.3748/wjg.14.6388

[53]

Wald A, Mueller-Lissner S, Kamm MA, et al. Survey of laxative use by adults with self-defined constipation in South America and Asia: a comparison of six countries. Aliment Pharmacol Ther. 2010; 31(2): 274-84. PMid:19832728.

[54]

Cheng C, Chan AOO, Hui WM, et al. Coping strategies, illness perception, anxiety and depression of patients with idiopathic constipation: a population-based study. Aliment Pharmacol Ther. 2003; 18(3): 319-26. PMid:12895216. https://doi.org/10.1046/j.1365-2036.2003.01663.x

[55]

Adibi P, Behzad E, Pirzadeh S, et al. Bowel habit reference values and abnormalities in young Iranian healthy adults. Dig Dis Sci. 2007; 52(8): 1810-3. PMid:17410463. https://doi.org/10.1007/s10620-006-9509-2

[56]

Sorouri M, Pourhoseingholi MA, Vahedi M, et al. Functional bowel disorders in Iranian population using Rome III criteria. Saudi J Gastroenterol. 2010; 16(3): 154-60. PMid:20616409. https://doi.org/10.4103/1319-3767.65183

[57]

Moezi P, Salehi A, Molavi H, et al. Prevalence of chronic constipation and its associated factors in pars cohort study: A study of 9000 adults in Southern Iran. Middle East J Dig Dis. 2018; 10(2): 75-83. PMid:30013755. https://doi.org/10.15171/mejdd.2018.94

[58]

Rajput M, Kumari Saini S. Prevalence of Constipation Among the General Population. Gastroenterol Nurs. 2014; 37(6): 425-9. PMid:25461464. https://doi.org/10.1097/SGA.0000000000000074

[59]

Herz MJ, Kahan E, Zalevski S, et al. Constipation: a different entity for patients and doctors. Family Practice. 1996; 13(2): 156-9. PMid:8732327. https://doi.org/10.1093/fampra/13.2.156

[60]

Chu H, Zhong L, Li H, et al. Epidemiology characteristics of constipation for general population, pediatric population, and elderly population in China. Gastroenterol Res Pract. 2014; 2014 (no pagination)(532734).

[61]

Iraji N, Keshteli AH, Sadeghpour S, et al. Constipation in Iran: Sepahan systematic review no. 5. Int J Prev Med. 2012; 3(4). PMid:22826768.

[62]

Chinzon D, Dias-Bastos TRP, Medeiros da Silva A, et al. Epidemiology of constipation in Sao Paulo, Brazil: a population-based study. Curr Med Res Opinion. 2015; 31(1): 57-64. PMid:25295483. https://doi.org/10.1185/03007995.2014.973485

[63]

Schmidt FM, de Gouveia Santos VL, de Cassia Domansky R, et al. Constipation: Prevalence and Associated Factors in Adults Living in Londrina, Southern Brazil. Gastroenterol Nurs. 2016; 39(3): 204-11. PMid:27258460. https://doi.org/10.1097/SGA.0000000000000224

[64]

Ng KS, Nassar N, Hamd K, et al. Prevalence of functional bowel disorders and faecal incontinence: An Australian primary care survey. Colorectal Dis. 2015; 17(2): 150-9. PMid:25359460. https://doi.org/10.1111/codi.12808

[65]

Koloski NA, Jones M, Young M, et al. Differentiation of functional constipation and constipation predominant irritable bowel syndrome based on Rome III criteria: a population-based study. Aliment Pharmacol Ther. 2015; 41(9): 856-66. PMid:25736433. https://doi.org/10.1111/apt.13149

[66]

Bytzer P, Howell S, Leemon M, et al. Low socioeconomic class is a risk factor for upper and lower gastrointestinal symptoms: a population based study in 15 000 Australian adults. Gut. 2001; 49(1): 66-72. PMid:11413112. https://doi.org/10.1136/gut.49.1.66

[67]

Boyce PM, Talley NJ, Burke C, et al. Epidemiology of the functional gastrointestinal disorders diagnosed according to Rome II criteria: An Australian population-based study. Int Med J. 2006; 36(1): 28-36. PMid:16409310. https://doi.org/10.1111/j.1445-5994.2006.01006.x

[68]

Koloski NA, Talley NJ, Boyce PM. Epidemiology and health care seeking in the functional GI disorders: a population-based study. Am J Gastroenterol. 2002; 97(9): 2290-9. PMid:12358247. https://doi.org/10.1111/j.1572-0241.2002.05783.x

[69]

Talley NJ, Boyce P, Jones M. Identification of distinct upper and lower gastrointestinal symptom groupings in an urban population. Gut. 1998; 42(5): 690-5. PMid:9659166. https://doi.org/10.1136/gut.42.5.690

[70]

Lam TCF, Kennedy ML, Chen FC, et al. Prevalence of faecal incontinence: obstetric and constipation-related risk factors; a population-based study. Colorectal Dis. 1999; 1(4): 197-203. PMid:23577806. https://doi.org/10.1046/j.1463-1318.1999.00044.x

[71]

Howell SC, Quine S, Talley NJ. Low social class is linked to upper gastrointestinal symptoms in an Australian sample of urban adults. Scand J Gastroenterol. 2006; 41(6): 657-66. PMid:16716963. https://doi.org/10.1080/00365520500442567

[72]

Suyasa IGPD, Paterson JB, Xiao LD, et al. Prevalence of constipation in communitydwelling older people in Indonesia. J Gastroenterol Hepatol. 2011; 4: 84.

[73]

Song HJ. Constipation in community-dwelling elders: Prevalence and associated factors. J Wound Ostomy Continence Nurs. 2012; 39(6): 640-5. PMid:22948493. https://doi.org/10.1097/WON.0b013e31826a4b70

[74]

Lopez Cara MA, Tarraga Lopez PJ, Cerdan Oliver M, et al. Constipation in the population over 50 years of age in Albacete province. Rev Esp Enferm Dig. 2006; 98(6): 449-59. PMid:16948544. https://doi.org/10.4321/S1130-01082006000600006

[75]

Andy UU, Vaughan CP, Burgio KL, et al. Shared Risk Factors for Constipation, Fecal Incontinence, and Combined Symptoms in Older U.S. Adults. J Am Geriatr Soc. 2016; 64(11): e183-e8. PMid:27783401. https://doi.org/10.1111/jgs.14521

[76]

Wolfsen CR, Barker JC, Mitteness LS. Constipation in the daily lives of frail elderly people. Arch Fam Med. 1993; 2(8): 853-8. PMid:8111515. https://doi.org/10.1001/archfami.2.8.853

[77]

Chaplin A, Curless R, Thomson R, et al. Prevalence of lower gastrointestinal symptoms and associated consultation behaviour in a British elderly population determined by face-to-face interview. Brit J Gen Pract. 2000; 50(459): 798-802. PMid:11127169.

[78]

Pit SW, Byles JE, Cockburn J. Prevalence of self-reported risk factors for medication misadventure among older people in general practice. J Eval Clin Pract. 2008; 14(2): 203-8. PMid:18284523. https://doi.org/10.1111/j.1365-2753.2007.00833.x

[79]

Werth BL, Williams KA, Pont LG. A longitudinal study of constipation and laxative use in a community-dwelling elderly population. Arch Gerontol Geriatr. 2015; 60(3): 418-24. PMid:25736738. https://doi.org/10.1016/j.archger.2015.02.004

[80]

Fragakis A, Zhou J, Mannan H, et al. Association between Drug Usage and Constipation in the Elderly Population of Greater Western Sydney Australia. Int J Environ Res Public Health. 2018; 15(2). PMid:29382180. https://doi.org/10.3390/ijerph15020226

[81]

Meiring PJ, Joubert G. Constipation in elderly patients attending a polyclinic. South African Med J. 1998; 88(7): 888-90. PMid:9698719.

[82]

Wong ML, Wee S, Pin CH, et al. Sociodemographic and lifestyle factors associated with constipation in an elderly Asian community. Am J Gastroenterol. 1999; 94(5): 1283-91. PMid:10235208. https://doi.org/10.1111/j.1572-0241.1999.01078.x

[83]

Harari D, Gurwitz JH, Avorn J, et al. How do older persons define constipation? Implications for therapeutic management. J Gen Intern Med. 1997; 12(1): 63-6. https://doi.org/10.1007/s11606-006-0009-z

[84]

Talley NJ, Fleming KC, Evans JM, et al. Constipation in an elderly community: a study of prevalence and potential risk factors. Am J Gastroenterol. 1996; 91(1): 19-25. PMid:8561137.

[85]

Stewart RB, Moore MT, Marks RG, et al. Correlates of constipation in an ambulatory elderly population. Am J Gastroenterol. 1992; 87(7): 859-64. PMid:1615939.

[86]

Whitehead WE, Drinkwater D, Cheskin LJ, et al. Constipation in the elderly living at home. Definition, prevalence, and relationship to lifestyle and health status. J Am Geriatr Soc. 1989; 37(5): 423-9. PMid:2539405. https://doi.org/10.1111/j.1532-5415.1989.tb02638.x

[87]

Lindeman RD, Romero LJ, Liang HC, et al. Do elderly persons need to be encouraged to drink more fluids? J Gerontol A Biol Sci Medl Sci. 2000; 55(7): M361-5.

[88]

Campbell AJ, Busby WJ, Horwath CC. Factors associated with constipation in a community based sample of people aged 70 years and over. J Epidemiol Community Health. 1993; 47(1): 23-6. PMid:8382251. https://doi.org/10.1136/jech.47.1.23

[89]

Wong RK, Palsson OS, Turner MJ, et al. Inability of the Rome III criteria to distinguish functional constipation from constipation-subtype irritable bowel syndrome. Am J Gastroenterol. 2010; 105(10): 2228-34. PMid:20502449. https://doi.org/10.1038/ajg.2010.200

[90]

Ford AC, Bercik P, Morgan DG, et al. Characteristics of functional bowel disorder patients: A cross-sectional survey using the Rome III criteria. Aliment Pharmacol Ther. 2014; 39(3): 312-21. PMid:24308816. https://doi.org/10.1111/apt.12573

[91]

Siah KTH, Wong RK, Whitehead WE. Chronic constipation and constipation-predominant IBS: Separate and distinct disorders or a spectrum of disease? Gastroenterol Hepatol. 2016; 12(3): 171-8.

[92]

Aziz I, Palsson OS, Tornblom H, et al. The prevalence and impact of overlapping Rome IV-diagnosed functional gastrointestinal disorders on somatization, quality of life, and healthcare utilization: A cross-sectional general population study in three countries. Am J Gastroenterol. 2018; 113(1): 86-96. PMid:29134969. https://doi.org/10.1038/ajg.2017.421

[93]

Johanson JF. Geographic distribution of constipation in the United States. Am J Gastroenterol. 1998; 93(2): 188-91. PMid:9468239. https://doi.org/10.1111/j.1572-0241.1998.00188.x

[94]

Lacy BE, Mearin F, Chang L, et al. Bowel disorders. Gastroenterology. 2016; 150(6): 1393-407. PMid:27144627. https://doi.org/10.1053/j.gastro.2016.02.031

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