Reprogramming of lipid droplets by host cells as a defense mechanism against viral infection
Zheng Chunfu
Journal of Clinical and Translational Research ›› 2025, Vol. 11 ›› Issue (1) : 82 -84.
Reprogramming of lipid droplets by host cells as a defense mechanism against viral infection
A recent study revealed the crucial roles of host cells in reprogramming lipid droplet (LD) synthesis to resist viral infection. Understanding the molecular mechanisms of host resistance to viral infection is necessary to develop safe and effective strategies to control viral infection. This study provides a thorough examination of the interplay between the transcription factor YY1 and LD synthesis in the context of viral infection, with potential implications for both fundamental research and practical applications in the swine industry.
Viral infection / Lipid droplet / Host cell reprogramming / Antiviral mechanism
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