From vitality to vulnerability: the impact of oxygen on cardiac function and regeneration

References

[1] D’Oria R,Leonardini A.The role of oxidative stress in cardiac disease: from physiological response to injury factor.Oxid Med Cell Longev2020;2020:5732956 PMCID:PMC7244977

[2] Puente BN,Muralidhar SA.The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.Cell2014;157:565-79 PMCID:PMC4104514

[3] Ali SR,Menendez-Montes I.Hypoxia-induced stabilization of HIF2A promotes cardiomyocyte proliferation by attenuating DNA damage.J Cardiovasc Aging2024;4:11

[4] Singh BN,Garay BI.Proliferation and maturation: Janus and the art of cardiac tissue engineering.Circ Res2023;132:519-40 PMCID:PMC9943541

[5] Guo Y.Cardiomyocyte maturation: new phase in development.Circ Res2020;126:1086-106 PMCID:PMC7199445

[6] Nakada Y,Thet S.Hypoxia induces heart regeneration in adult mice.Nature2017;541:222-7

[7] Zong H,Su HH,Luo L.Mosaic analysis with double markers in mice.Cell2005;121:479-92

[8] Cardoso AC,Savla JJ.Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression.Nat Metab2020;2:167-78

[9] Magadum A,Kurian AA.Pkm2 regulates cardiomyocyte cell cycle and promotes cardiac regeneration.Circulation2020;141:1249-65 PMCID:PMC7241614

[10] Li X,Günther S.Inhibition of fatty acid oxidation enables heart regeneration in adult mice.Nature2023;622:619-26 PMCID:PMC10584682

[11] Ang KL,Reuter S.Limitations of conventional approaches to identify myocyte nuclei in histologic sections of the heart.Am J Physiol Cell Physiol2010;298:C1603-9 PMCID:PMC2902296

[12] Bergmann O,Bernard S.Evidence for cardiomyocyte renewal in humans.Science2009;324:98-102 PMCID:PMC2991140

[13] Senyo SE,Pizzimenti CL.Mammalian heart renewal by pre-existing cardiomyocytes.Nature2013;493:433-6 PMCID:PMC3548046