ASGR1 and cholesterol: connecting the dots

The Journal of Cardiovascular Aging ›› 2023, Vol. 3 ›› Issue (2) :15 DOI: 10.20517/jca.2023.8

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Hilma Holm. ASGR1 and cholesterol: connecting the dots. The Journal of Cardiovascular Aging, 2023, 3(2): 15 DOI:10.20517/jca.2023.8

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[1]	Ference BA,Graham I.Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel.Eur Heart J2017;38:2459-72 PMCID:PMC5837225

[2]	Bjornsson E,Halldorsson GH.Lifelong reduction in LDL (low-density lipoprotein) cholesterol due to a gain-of-function mutation in LDLR.Circ Genom Precis Med2021;14:e003029

[3]	Mach F,Catapano AL.2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.Eur Heart J2020;41:111-88

[4]	Ramsaran E,Sundaresan D.Adherence to blood cholesterol treatment guidelines among physicians managing patients with atherosclerotic cardiovascular disease.Am J Cardiol2019;124:169-75

[5]	Nioi P,Thorleifsson G.Variant ASGR1 associated with a reduced risk of coronary artery disease.N Engl J Med2016;374:2131-41

[6]	Wang JQ,Hu A.Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.Nature2022;608:413-20

[7]	Helgadottir A,Alexandersson KF.Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease.Eur Heart J2020;41:2618-28 PMCID:PMC7377579