Microneedle technology- an insight into advancements, latest scholarly and patent data

Abstract

Microneedles (MN) have been used to deliver small molecular weight drugs, nucleotides, DNA, peptides, proteins, and even viruses that have been turned off. Over the past ten years, different kinds of MN have been made using several different production methods. Different kinds of materials have been used to make different shapes of microneedles. Using these MNs, different ways of putting drugs through the skin with microneedles have been tried. After a short introduction to microneedles for transdermal use, this review talks about the different kinds, how they are made, and recent improvements in MN delivery. In a separate part of this review, patents survey on MN using databases such as USPTO (United States Patent and Trademark Office), EPO (European Patent Office), and WIPO (World Intellectual Property Organization), etc. are discussed in detail. We talked about recent improvements to MN-based methods for getting drugs and vaccines to people. Because MN worked so well, there was a lot of interest in taking advantage of the opportunities, as patent data shows. With a current worldwide perspective, the current analysis confirms the overall evolution and unexplored areas of MN research and makes microneedle-based (trans)dermal drug delivery systems for effective therapeutic effects.

Keywords

Microneedles / Transdermal delivery / Patent search / Clinical trials

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2024 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.