Influence of national centralized drug procurement policy on the use of antibiotics in pediatric inpatients

Abstract

Objective: To explore the safety and efficacy of centrally procured antimicrobial drugs in the pediatric population, the impact of centrally procured policies on pediatric antimicrobial drug use and drug costs, and to make recommendations for hospitals to balance better the relationship between centralized procurement policies and antimicrobial drug management.

Methods: The data on the use of antimicrobial drugs and adverse reactions reported by inpatients in our hospital for half a year before and after centralized drug procurement were collected. Changes in the intensity, structure and utilization rate of antibacterial drugs, incidence of adverse reactions and drug costs, average length of stay, cure rate and improvement rate of patients before and after centralized procurement were compared. An electronic questionnaire survey was conducted on the cognition of clinical medical staff on the use of antibacterial drugs before and after centralized drug procurement.

Results: 1. Centralized antibacterial drugs are widely used in our hospital, and there is no obvious difference in safety and effectiveness from non-centralized drugs. 2. The centralized procurement policy significantly reduces antimicrobial drug costs but increases non-antimicrobial drug costs. 3. The intensity and utilization rate of antimicrobial drugs has stayed the same after the centralized procurement policy, but the drug structure changed.

Conclusion: There is still some prejudice among medical professionals and the public towards centralized antibacterial drugs, and positive guidance should be strengthened. The implementation of the centralized procurement policy needs corresponding management measures to ensure the rational use of antimicrobial drugs in clinic.

Keywords

Pediatrics / Antimicrobial drugs / Centralized procurement / Rational drug use

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2023 2023 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).