Expert consensus on early orthodontic treatment of class III malocclusion

Xin Zhou , Si Chen , Chenchen Zhou , Zuolin Jin , Hong He , Yuxing Bai , Weiran Li , Jun Wang , Min Hu , Yang Cao , Yuehua Liu , Bin Yan , Jiejun Shi , Jie Guo , Zhihua Li , Wensheng Ma , Yi Liu , Huang Li , Yanqin Lu , Liling Ren , Rui Zou , Linyu Xu , Jiangtian Hu , Xiuping Wu , Shuxia Cui , Lulu Xu , Xudong Wang , Songsong Zhu , Li Hu , Qingming Tang , Jinlin Song , Bing Fang , Lili Chen

International Journal of Oral Science ›› 2025, Vol. 17 ›› Issue (1) : 20

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International Journal of Oral Science ›› 2025, Vol. 17 ›› Issue (1) : 20 DOI: 10.1038/s41368-025-00357-9
Review Article

Expert consensus on early orthodontic treatment of class III malocclusion

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Abstract

The prevalence of Class III malocclusion varies among different countries and regions. The populations from Southeast Asian countries (Chinese and Malaysian) showed the highest prevalence rate of 15.8%, which can seriously affect oral function, facial appearance, and mental health. As anterior crossbite tends to worsen with growth, early orthodontic treatment can harness growth potential to normalize maxillofacial development or reduce skeletal malformation severity, thereby reducing the difficulty and shortening the treatment cycle of later-stage treatment. This is beneficial for the physical and mental growth of children. Therefore, early orthodontic treatment for Class III malocclusion is particularly important. Determining the optimal timing for early orthodontic treatment requires a comprehensive assessment of clinical manifestations, dental age, and skeletal age, and can lead to better results with less effort. Currently, standardized treatment guidelines for early orthodontic treatment of Class III malocclusion are lacking. This review provides a comprehensive summary of the etiology, clinical manifestations, classification, and early orthodontic techniques for Class III malocclusion, along with systematic discussions on selecting early treatment plans. The purpose of this expert consensus is to standardize clinical practices and improve the treatment outcomes of Class III malocclusion through early orthodontic treatment.

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Xin Zhou, Si Chen, Chenchen Zhou, Zuolin Jin, Hong He, Yuxing Bai, Weiran Li, Jun Wang, Min Hu, Yang Cao, Yuehua Liu, Bin Yan, Jiejun Shi, Jie Guo, Zhihua Li, Wensheng Ma, Yi Liu, Huang Li, Yanqin Lu, Liling Ren, Rui Zou, Linyu Xu, Jiangtian Hu, Xiuping Wu, Shuxia Cui, Lulu Xu, Xudong Wang, Songsong Zhu, Li Hu, Qingming Tang, Jinlin Song, Bing Fang, Lili Chen. Expert consensus on early orthodontic treatment of class III malocclusion. International Journal of Oral Science, 2025, 17(1): 20 DOI:10.1038/s41368-025-00357-9

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