In-vivo optical imaging in head and neck oncology: basic principles, clinical applications and future directions

Abstract

New imaging technologies hold promise for early detection and improved treatment of head and neck cancers, the sixth most common type of cancer worldwide. The first line of treatment is surgery, but complete tumor removal can be difficult when operating on this sensitive region. Improving methods for early detection and clear visualization of tumor edges could help minimize loss of healthy tissue. Eben Rosenthal at Stanford University in California and Yi Li at the West China School of Stomatology in Chengdu City reviewed new technologies, many of which use fluorescence to identify tumor tissue. Some techniques even allow real-time visualization of tumor edges in the operating theatre. The researchers discuss the applications and limitations of these new technologies and highlight promising future directions, including increasing the commercial availability and decreasing the size of the instruments.

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