Second premolar agenesis is associated with mandibular form: a geometric morphometric analysis of mandibular cross-sections

Abstract

Common developmental cues probably underlie both premolar tooth agenesis and the shape of the jawbone. About 3% of the population never develop a lower second premolar tooth. What is the relationship between missing teeth and jawbone shape? To find out, a team led by Michael Bertl from the University Clinic of Dentistry in Vienna, Austria, measured anatomical landmark coordinates in the jawbones of 150 patients. They found that people missing a lower second premolar, whether or not their primary second molars had been extracted, had morphological differences that extended across the whole jawbone, pointing to genetic and epigenetic effects affecting the growth of both craniofacial bones and teeth.

Keywords

agenesis / cross-sections / geometric morphometrics / mandibular form

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