Novel rechargeable calcium phosphate nanoparticle-containing orthodontic cement

Abstract

An orthodontic cement showing sustained release of calcium (Ca) and phosphate (P) ions may promote enamel remineralization. Fixed orthodontic attachments allow bacteria to accumulate causing enamel demineralization and white spot lesions. Dental cements formed from calcium phosphate (CaP) composites can release ions and prevent demineralization, however, these composites lack the required mechanical strength. Now, Hockin Xu at the University of Maryland, US, and colleagues report a nanoparticle-containing composite that shows sustained release of Ca/P ions over 14 days with an enamel bond strength similar to commercial orthodontic cements. The cement, formed from CaP nanoparticles mixed with a methacrylate-based resin, can be replenished with ions by placing it in Ca and P solutions, which may be possible using mouthwash. The CaP nanoparticle-based material was repeatedly re-charged with no observed decrease in ion release.

Keywords

bond strength / calcium phosphate nanoparticles / calcium phosphate ion rechargeability / long-term ion release / orthodontic cement / white spot lesions

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