Cetylpyridinium chloride mouth rinses alleviate experimental gingivitis by inhibiting dental plaque maturation

Abstract

Daily use of a mouth rinse can effectively treat the gum disease gingivitis by reducing oral bacterial diversity and plaque formation. Dental plaque is a biofilm formed from multiple bacteria that can cause gingivitis and other infections if it is allowed to mature. Rui Li at Procter & Gamble International Operations in Singapore, and coworkers across China conducted a randomized trial on 91 adults to clarify the response of oral bacteria to treatment with cetylpyridinium chloride-based (CPC) mouth rinse. After intensive oral hygiene treatment for 21 days, the participants were split into a control group (given only water) and a CPC rinse group. Both groups followed a daily rinsing routine for three weeks. The team found the CPC rinse inhibited 17 gingivitisassociated bacteria, and significantly reduced plaque formation by disrupting bacterial interactions.

Keywords

cetylpyridinium chloride / oral microbiota / oral rinse

References

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