Evaluation of three-dimensional biofilms on antibacterial bonding agents containing novel quaternary ammonium methacrylates

Abstract

Dental resins incorporating antibacterial agents could help to destroy the bacterial biofilm responsible for tooth decay, new research shows. By forming a biofilm on surfaces such as teeth, bacterial cells strengthen their chances of survival. To avoid secondary tooth decay following tooth restoration, it is important to minimize the biofilm growth of Streptococcus mutans, bacteria commonly associated with tooth decay. Hockin Xu at the University of Maryland and co-workers across USA and China investigated the effects of new antibacterial dental resins containing various ammonium salts. Their work focused on bacterial survival in different areas of the biofilm. The team found that the most effective resin was that incorporating an ammonium salt with a carbon backbone chain length of 16. This resin killed bacteria throughout the whole thickness of the biofilm.

Keywords

alkyl chain length / antibacterial bonding agent / dental caries / quaternary ammonium methacrylate / Streptococcus mutans / three-dimensional biofilm

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