Residual activity of cetrimide and chlorhexidine on Enterococcus faecalis-infected root canals

Abstract

Cleaning root canals with chlorhexidine antiseptic leaves a sustained residual antimicrobial effect, research from Spain shows. Root canal surgery carries a high risk of infection: the bacteria Enterococcus faecalis is commonly found following the procedure. Effective irrigation of root canals during root canal treatment disinfects the area and can provide a barrier to future infection by leaving an antimicrobial residue to attack remaining bacteria. To verify the most effective treatment, Carmen Maria Ferrer-Luque and colleagues at the University of Granada compared three irrigation solutions on root canals infected with E. faecalis. After 50 days, the team found significant bacterial growth on 69% of roots treated with weak solutions (0.2%) of cetrimide and chlorhexidine. A more potent chlorhexidine solution (2%), however, indicated a longer-lasting residual effect, with E. faecalis growth on less than 35% of roots.

Keywords

antimicrobial effects / biofilms / cetrimide / chlorhexidine / Enterococcus faecalis / final irrigation / residual activity

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