Efficacy of two calcium phosphate pastes on the remineralization of artificial caries: a randomized controlled double-blind in situ study

Abstract

A comparative study suggests that fluoride toothpaste is as effective at promoting cavity repair as more expensive alternative treatments. Tooth demineralization accelerates the formation of dental caries, and consumers can now choose between several calcium- and phosphate-rich compounds that were developed to augment the reparative properties of conventional fluoride toothpastes. Somkamol Vanichvatana and Prim Auychai of Chulalongkorn University in Thailand studied the effectiveness of two of these products, CPP-ACPF and f TCP, with a group of volunteers. They confirmed that both compounds promoted remineralization in tooth enamel with artificially induced caries. However, neither product meaningfully outperformed fluoride toothpaste alone. In contrast to previous studies that have suggested some additional benefit, the researchers had volunteers use CPP-ACPF and f TCP directly according to manufacturer's specifications. Therefore, fluoride toothpaste may generally offer a more economical approach to treating caries.

Keywords

Clinpro / casein phosphopeptide-amorphous calcium phosphate / fluoride / functionalized tricalcium phosphate / remineralization

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