Periodontopathogen profile of healthy and oral lichen planus patients with gingivitis or periodontitis

Abstract

Patients with oral lichen planus (OLP) have higher rates of infection with microbes that cause periodontal disease, researchers in Turkey have shown. The findings could help to explain the causes of this poorly understood chronic inflammatory condition that produces red or lacy white lesions in the mouth. Researchers had characterized the association between OLP and infection with herpes-family viruses, but not with pathogenic bacteria. Abdullah seckin Ertugrul of the Yuzuncu Yil University and co-workers used genetic methods, which can identify anaerobic bacteria more efficiently than culturing, to screen the microbes in plaque samples from patients with OLP and without the condition. The OLP patients had significantly higher rates of infection with pathogens such as Porphyromonas gingivalis and Treponema denticola. The authors recommend long-term studies to investigate whether these microbes play a direct role in causing OLP.

Keywords

Aggregatibacter actinomycetemcomitans / oral lichen planus / Porphyromonas gingivalis / Prevotella intermedia / Tannerella forsythia / Treponema denticola

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