A case of hemangiopericytoma of the soft palate with articulate disorder and dysphagia

Abstract

We report a case of hemangiopericytoma of the soft palate of 60-year-old patient, who noticed a mass of the soft palate and experienced difficulty in speaking. We found a pediculate, hard, elastic mass measuring 38 mm (cross-sectional diameter). Computed tomography (CT) scans and dynamic magnetic resonance imaging (MRI) confirmed irregularly shaped mass and revealed a heterogeneous internal composition, consistent with vascular tumors. We excised the tumor under general anesthesia. Histopathological diagnosis was based on positive immunoreactivity of CD99 and vimentin and weak, positive staining of CD34. Three and half years following tumor excision, there is no recurrence or metastasis.

Keywords

dysphagia / hemangiopericytoma / histopathological diagnosis

References

[1] Enzinger FM, Weiss SW. Soft Tissue Tumors, 1988 St Louis 596-613.

[2] Unni KK, Ivins JC, Beabout JW. Hemangioma, hemangiopericytoma, and hemangioendothelioma (angiosarcoma) of bone. Cancer, 1971, 27(6): 1403-1414.

[3] Rodríguez-Gil Y, González MA, Carcavilla CB. Lines of cell differentiation in solitary fibrous tumor: an ultrastructural and immunohistochemical study of 10 cases. Ultrastruct Pathol, 2009, 33(6): 274-285.

[4] Stout AP, Murray MR. Hemangiopericytoma: a vascular tumor featuring Zimmermann’s pericyte. Ann Surg, 1942, 116(1): 26-33.

[5] Backwinkel KD, Diddams JA. Hemangiopericytoma. Report of a case and comprehensive review of the literature. Cancer, 1970, 25(4): 896-901.

[6] Enzinger FM, Smith BH. Hemangiopericytoma. An analysis of 106 cases. Hum Pathol, 1976, 7(1): 61-82.

[7] O'brien P, Brasfield RD. Hemangiopericytoma. Cancer, 1965, 18: 249-252.

[8] Hogle WP. Malignant hemangiopericytoma: a clinical overview and case study. Clin J Oncol Nurs, 2003, 7(1): 57-62.

[9] Fletcher CD, Unni K, Mertens F. World health organization. Classification of tumours, pathology and genetics, tumours of soft tissue and bone, 2002 Lyon 432.

[10] Stout AP. Hemangiopericytoma: a study of twenty five new cases. Cancer, 1949, 2(6): 1027-1035.

[11] Morita N, Sakamoto T, Yamamoto M. Hemangiopericytoma of the oral cavity. J Oral Maxillofac Surg, 1982, 40(5): 305-307.

[12] Goldwasser MS, Daw JL. Hemangiopericytoma of the palate: case report. J Oral Maxillofac Surg, 1990, 48(2): 211-215.

[13] Kothari PS, Murphy M, Howells GL. Hemangiopericytoma: a report of two cases arising on the lip. Br J Oral Maxillofac Surg, 1996, 34(5): 454-456.

[14] Terakado M, Uehara T, Takigawa T. A case of hemangiopericytoma of the buccal mucosa. J Nihon Univ Sch Dent, 1997, 39(4): 211-215.

[15] Carew JF, Singh B, Kraus DH. Hemangiopericytoma of the head and neck. Laryngoscope, 1999, 109(9): 1409-1411.

[16] Billings KR, Fu YS, Calcaterra TC. Hemangiopericytoma of the head and neck. Am J Otolaryngol, 2000, 21: 238-243.

[17] Moriya S, Tei K, Notani K. Malignant hemangiopericytoma of the head and neck: a report of 3 cases. J Oral Maxillofac Surg, 2001, 59(3): 340-345.

[18] Hiraumi H, Kitajiri S, Hirose T. Radiosensitive hemangiopericytoma in the soft palate. Auris Nases Larynx, 2002, 29(1): 95-97.

[19] Orlando GJ, Gil MM, Olivier R. Giant hemangiopericytoma of mandible: a propos of a case: a variant of the surgical technique for protection of the articular fosse. J Craniofac Surg, 2006, 17(3): 523-527.

[20] Batsakis JG, Rice DH. The Pathology of head and neck tumors: vasoformative tumors, part 9B. Head Neck Surg, 1981, 3(4): 326-339.