Rapid 3D reconstruction in fetal ultrasound imaging using artificial intelligence and medical 3D printing

Wenjuan Zhang , Jiahe Liang , Linbin Lai , Zewen Zhang , Yitong Guo , Na Hou , Zekai Zhang , Zhuojun Mao , Tiesheng Cao , Yu Li , Lijun Yuan , Airong Qian

International Journal of Bioprinting ›› 2025, Vol. 11 ›› Issue (4) : 242 -255.

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International Journal of Bioprinting ›› 2025, Vol. 11 ›› Issue (4) : 242 -255. DOI: 10.36922/IJB025200192
RESEARCH ARTICLE
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Rapid 3D reconstruction in fetal ultrasound imaging using artificial intelligence and medical 3D printing

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Abstract

Congenital heart disease (CHD) has been one of the most serious problems in newborns. For fetal heart health care, 3D modeling and printing technology have been adopted in the diagnosis of CHD during antenatal care. However, the development of 3D printing techniques and their clinical applications have been hindered by the manual processing of ultrasound (US) volume data in clinical practice. To overcome this problem, we present an interactive semi-automatic method based on deep learning that uses manual processing results from expert sonographers for training. The accuracy, interpretability, and variability of the performances were evaluated on the validation set. The results demonstrated that compared with a physician with less than 3 years of experience, a better Faster- region-based convolutional neural network-based threshold was achieved using our proposed fetal heart reconstruction technique (FRT), with enhanced performance based on the outflow tract view and three-vessel view. No significant difference was found among the clinical parameters, in proportion, measured from the model rebuilt using FRT and US volume data. Furthermore, the reconstruction time of the fetal heart blood pool model was reduced from approximately 5 h to 5 min. Our results indicate that deep learning has the ability to process US data accurately, representing an important step towards the reconstruction of the fetal heart digital model, which is critical for advancing clinical diagnosis and treatment of CHD during pregnancy.

Keywords

3D printing technology / Congenital heart disease / Deep learning / Reconstruction of ultrasound imaging data

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Wenjuan Zhang, Jiahe Liang, Linbin Lai, Zewen Zhang, Yitong Guo, Na Hou, Zekai Zhang, Zhuojun Mao, Tiesheng Cao, Yu Li, Lijun Yuan, Airong Qian. Rapid 3D reconstruction in fetal ultrasound imaging using artificial intelligence and medical 3D printing. International Journal of Bioprinting, 2025, 11(4): 242-255 DOI:10.36922/IJB025200192

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Funding

This work was supported by the Key Research and Development Project of Shaanxi Province (2021LLRH-08).

Conflict of interest

The authors declare that they have no competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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