Brassica vegetables—an undervalued nutritional goldmine

Xiaomeng Zhang , Qiong Jia , Xin Jia , Jie Li , Xiaoxue Sun , Leiguo Min , Zhaokun Liu , Wei Ma , Jianjun Zhao

Horticulture Research ›› 2025, Vol. 12 ›› Issue (2) : 302

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Horticulture Research ›› 2025, Vol. 12 ›› Issue (2) :302 DOI: 10.1093/hr/uhae302
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Brassica vegetables—an undervalued nutritional goldmine
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Abstract

The genus Brassica includes six species and over 15 types of vegetables that are widely cultivated and consumed globally. This group of vegetables is rich in bioactive compounds, including glucosinolates, vitamins (such as vitamin C, folate, tocopherol, and phylloquinone), carotenoids, phenols, and minerals, which are crucial for enriching diets and maintaining human health. However, the full extent of these phytonutrients and their significant health benefits remain to be fully elucidated. This review highlights the nutrient compositions and health advantages of Brassica vegetables and discusses the impacts of various processing methods on their nutritional value. Additionally, we discuss potential strategies for enhancing the nutrition of Brassica crops through agronomic biofortification, conventional breeding, and biotechnological or metabolic engineering approaches. This review lays the foundation for the nutritional improvement of Brassica crops.

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Xiaomeng Zhang, Qiong Jia, Xin Jia, Jie Li, Xiaoxue Sun, Leiguo Min, Zhaokun Liu, Wei Ma, Jianjun Zhao. Brassica vegetables—an undervalued nutritional goldmine. Horticulture Research, 2025, 12(2): 302 DOI:10.1093/hr/uhae302

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Acknowledgements

We are grateful to Yiguo Hong for his critical review and invaluable suggestions that significantly improved manuscript. This work was partially funded by the Innovative Research Group Project of Hebei Natural Science Foundation (grant number C2024204246), the National Natural Science Foundation of China (grant numbers 32372736 and 32330096), the Science and Technology Project of the Hebei Education Department (grant numbers YJZ2024001 and JZX2024001), and the Hebei Natural Science Foundation (grant number C2023204308), the Key Research and Development Program of Hebei (grant number 21326311D-2). We would also like to thank A&L Scientific Editing (www.alpublish.com) for their linguistic assistance during the preparation of this manuscript.

Author contributions

X.Z., Q.J., X.J., and X.S. prepared the manuscript. X.Z., Q.J., and X.J. wrote the paper. J.L., L.M., Z.L., W.M., and J.Z. revised the Manuscript. All authors read and approved the final manuscript.

Conflict of interest statement

The authors declare no conflict of interest.

References

[1]

Cheng F, Wu J, Cai C. et al. Genome resequencing and compar-ative variome analysis in a Brassica rapa and Brassica oleracea collection. Sci Data. 2016;3:160119

[2]

Wu J, Liang J, Lin R. et al. Investigation of brassica and its relative genomes in the post-genomics era. Hortic Res. 2022;9:uhac182

[3]

Niu Y, Liu Q, He Z. et al. A Brassica carinata pan-genome platform for brassica crop improvement. Plant Commun. 2024;5:100725

[4]

SunB, TianYX, JiangM. et al. Variation in the main health-promoting compounds and antioxidant activity of whole and individual edible parts of baby mustard (Brassica juncea var. gemmifera). RSC Adv. 2018;8:33845-54

[5]

Nagaharu U. Genome analysis in brassica with special reference to the experimental formation of B. napus and peculiar mode of fertilization. Japan J Bot. 1935;7:389-452

[6]

Arias T, Beilstein MA, Tang M. et al. Diversification times among brassica (Brassicaceae) crops suggest hybrid formation after 20 million years of divergence. Am J Bot. 2014;101:86-91

[7]

Zhu B, Liang Z, Zang Y. et al. Diversity of glucosinolates among common Brassicaceae vegetables in China. Hortic Plant J. 2023;9:365-80

[8]

Al-Shehbaz IA, Beilstein MA, Kellogg EA. Systematics and phy-logeny of the Brassicaceae (Cruciferae): an overview. Plant Syst Evol. 2006;259:89-120

[9]

Lagercrantz U. Comparative mapping between Arabidopsis thaliana and Brassica nigra indicate the brassica genomes have evolved through extensive genome replication accompanied by chromosome fusions and frequent rearrangements. Genetics. 1998;150:1217-28

[10]

Lagercrantz U, Lydiate D. Comparative genome mapping in brassica. Genetics. 1996;144:1903-10

[11]

Warwick SI, Black LD. Molecular phylogenies from theory to application in brassica and allies (tribe Brassiceae, Brassi-caceae). Opera Bot. 1997;97:159-68

[12]

Liu Z, Fu Y, Wang H. et al. The high-quality sequencing of the Brassica rapa ’XiangQingCai’ genome and exploration of genome evolution and genes related to volatile aroma. Hortic Res. 2023;10:uhad187

[13]

Mabuchi R, Tanaka M, Nakanishi C et al. Analysis of primary metabolites in cabbage ( Brassica oleracea var. capitata)varieties correlated with antioxidant activity and taste attributes by metabolic profiling. Molecules. 2019;24:4282

[14]

Yin X, Yang D, Zhao Y. et al. Differences in pseudogene evolution contributed to the contrasting flavors of turnip and Chiifu, two Brassica rapa subspecies. Plant Commun. 2023;4:100427

[15]

Jeon J, Lim CJ, Kim JK. et al. Comparative metabolic profiling of green and purple pakchoi (Brassica Rapa Subsp. Chinensis). Molecules. 2018;23:1613

[16]

Artemeva A, Soloveva AE. Quality evaluation of some cultivar types of leafy Brassica rapa. Acta Hortic. 2006;706:121-8

[17]

Favela-González KM, Hernández-Almanza AY,De la Fuente-Salcido NM. The value of bioactive compounds of crucifer-ous vegetables (Brassica) as antimicrobials and antioxidants: a review. J Food Biochem. 2020;44:e13414

[18]

Zhao Y, Yue Z, Zhong X. et al. Distribution of primary and sec-ondary metabolites among the leaf layers of headed cabbage (Brassica oleracea var. capitata). Food Chem. 2020;312:126028

[19]

Brennan P, Hsu CC, Moullan N et al. Effect of cruciferous veg-etables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach. Lancet. 2005;366:1558-60

[20]

Herr I, Büchler MW. Dietary constituents of broccoli and other cruciferous vegetables: implications for prevention and ther-apyofcancer. Cancer Treat Rev. 2010;36:377-83

[21]

Higdon JV, Delage B, Williams DE et al. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanis-tic basis. Pharmacol Res. 2007;55:224-36

[22]

Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer. 2002;42:1-9

[23]

Boeing H, Bechthold A, Bub A. et al. Critical review: vegetables and fruit in the prevention of chronic diseases. Eur J Nutr. 2012;51:637-63

[24]

Bradbury KE, Appleby PN, Key TJ. Fruit, vegetable, and fiber intake in relation to cancer risk: findings from the European prospective investigation into cancer and nutrition (EPIC). Am J Clin Nutr. 2014;100:394S-8

[25]

Martin C, Butelli E, Petroni K et al. How can research on plants contribute to promoting human health? Plant Cell. 2011;23:1685-99

[26]

Mozaffarian D, Hao T, Rimm EB. et al.Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med. 2011;364:2392-404

[27]

Li J, Martin C, Fernie A. Biofortification’s contribution to miti-gating micronutrient deficiencies. Nat Food. 2024;5:19-27

[28]

Verkerk R, Schreiner M, Krumbein A et al. Glucosinolates in Brassica vegetables: the influence of the food supply chain on intake, bioavailability and human health. Mol Nutr Food Res. 2009;53:S219

[29]

Aggarwal BB, Ichikawa H. Molecular targets and anti-cancer potential of Indole-3-Carbinol and its derivatives. Cell Cycle. 2005;4:1201-15

[30]

Bell L, Oloyede OO, Lignou S. et al. Taste and flavor perceptions of Glucosinolates, Isothiocyanates, and related compounds. Mol Nutr Food Res. 2018;62:e1700990

[31]

Felker P, Bunch R, Leung AM. Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothy-roidism. Nutr Rev. 2016;74:248-58

[32]

Jakubikova J, Bao Y, Sedlak J. Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines. Anticancer Res. 2005;25:3375-86

[33]

Ahn J, Lee H, Im SW. et al. Allyl isothiocyanate ameliorates insulin resistance through the regulation of mitochondrial function. J Nutr Biochem. 2014;25:1026-34

[34]

Mithen R, Faulkner K, Magrath R et al. Development of isothiocyanate-enriched broccoli, and its enhanced ability to induce phase 2 detoxification enzymes in mammalian cells. Theor Appl Genet. 2003;106:727-34

[35]

Wu CL, Huang AC, Yang JS. et al. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunc-tion and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells. J Orthop Res. 2011;29:1199-209

[36]

Arora R, Kumar R, Mahajan J et al. 3-Butenyl isothiocyanate: a hydrolytic product of glucosinolate as a potential cytotoxic agent against human cancer cell lines. J Food Sci Tech. 2016;53:3437-45

[37]

Fahey JW, Zalcmann AT, Talalay P. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. Phytochemistry. 2001;56:5-51

[38]

Srivastava SK, Xiao D, Lew KL. et al. Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo. Carcinogenesis. 2003;24:1665-70

[39]

Riedl MA, Saxon A, Diaz-Sanchez D. Oral sulforaphane increases phase II antioxidant enzymes in the human upper airway. Clin Immunol. 2009;130:244-51

[40]

Zhang Y. Allyl isothiocyanate as a cancer chemopre-ventive phytochemical. Mol Nutr Food Res. 2010;54:127-35

[41]

Zhang Y, Du J, Jin L. et al. Iberverin exhibits antineoplastic activities against human hepatocellular carcinoma via DNA damage-mediated cell cycle arrest and mitochondrial-related apoptosis. Front Pharmacol. 2023;14:1326346

[42]

Jang M, Hong E, Kim GH. Evaluation of antibacterial activity of 3-butenyl, 4-pentenyl, 2-phenylethyl, and benzyl isothiocyanate in Brassica vegetables. J Food Sci. 2010;75:M412-6

[43]

Melchini A, Traka MH, Catania S et al. Antiproliferative activity of the dietary isothiocyanate erucin, a bioactive compound from cruciferous vegetables, on human prostate cancer cells. Nutr Cancer. 2013;65:132-8

[44]

Cho HJ, Lee KW, Park JH. Erucin exerts anti-inflammatory properties in murine macrophages and mouse skin: possible mediation through the inhibition of NFKB signaling. Int J Mol Sci. 2013;14:20564-77

[45]

Kim YS, Milner JA. Targets for indole-3-carbinol in cancer pre-vention. J Nutr Biochem. 2005;16:65-73

[46]

Neave AS, Sarup SM, Seidelin M et al. Characterization of the N-methoxyindole-3-carbinol (NI3C)-induced cell cycle arrest in human colon cancer cell lines. Toxicol Sci. 2005;83:126-35

[47]

Dey M, Ribnicky D, Kurmukov AG et al. In vitro and in vivo anti-inflammatory activity of a seed preparation contain-ing Phenethylisothiocyanate. J Pharmacol Exp Ther. 2006;317:326-33

[48]

Hong E, Kim GH. Anti-cancer and antimicrobial activities of β-phenylethyl isothiocyanate in Brassica rapa L. Food Sci Technol Res. 2008;14:377-82

[49]

Gupta P, Wright SE, Kim SH. et al. Phenethyl isothiocyanate: a comprehensive review of anti-cancer mechanisms. Biochim Biophys Acta. 2014;1846:405-24

[50]

Gwon MH, Im YS, Seo AR. et al. Phenethyl isothiocyanate pro-tects against high fat/cholesterol diet-induced obesity and atherosclerosis in C57BL/ 6 mice. Nutrients. 2020;12:3657

[51]

Holst B, Williamson G. A critical review of the bioavailability of glucosinolates and related compounds. Nat Prod Rep. 2004;21:425-47

[52]

Joseph MA, Moysich KB, Freudenheim JL et al. Cruciferous veg-etables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk. Nutr Cancer. 2004;50:206-13

[53]

Kim MK, Park JHY. Cruciferous vegetable intake and the risk of human cancer: epidemiological evidence: conference on ‘mul-tidisciplinary approaches to nutritional problems’ symposium on ‘nutrition and health’. Proc Nutr Soc. 2009;68:103-10

[54]

Wu QJ, Yang Y, Wang J. et al. Cruciferous vegetable consumption and gastric cancer risk: a meta-analysis of epidemiological studies. Cancer Sci. 2013;104:1067-73

[55]

Iahtisham, Ul H, Khan S, Awan KA. et al. Sulforaphane as a potential remedy against cancer: comprehensive mechanistic review. J Food Biochem. 2022;46:e13886

[56]

Zhang Y, Zhang W, Zhao Y. et al. Bioactive sulforaphane from cruciferous vegetables: advances in biosynthesis, metabolism, bioavailability, delivery, health benefits, and applications. Crit Rev Food Sci Nutr. 2024;1-21

[57]

Ahmad A, Sakr WA, Rahman KM. Anti-cancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy. Curr Drug Targets. 2010;11:652-66

[58]

Firestone GL, Sundar SN. Minireview: modulation of hormone receptor signaling by dietary anti-cancer indoles. Mol Endocrinol. 2009;23:1940-7

[59]

Sarkar FH, Li Y. Harnessing the fruits of nature for the devel-opment of multi-targeted cancer therapeutics. Cancer Treat Rev. 2009;35:597-607

[60]

Fahey JW, Stephenson KK, Wade KL. et al. Urease from heli-cobacter pylori is inactivated by sulforaphane and other isoth-iocyanates. Biochem Biophys Res Commun. 2013;435:1-7

[61]

Yanaka A, Fahey JW, Fukumoto A et al. Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in helicobacter pylori-infected mice and humans. Cancer Prev Res. 2009;2:353-60

[62]

Griffiths DW, Birch ANE, Hillman JR. Antinutritional com-pounds in the Brasi analysis, biosynthesis, chemistry and dietary effects. J Hortic Sci Biotechnol. 1998;73:1-18

[63]

Cartea ME, de Haro A, Obregón S et al. Glucosinolate variation in leaves of Brassica rapa crops. Plant Foods Hum Nutr. 2012;67:283-8

[64]

Wiesner M, Zrenner R, Krumbein A et al. Genotypic variation of the glucosinolate profile in pak choi (Brassica rapa ssp. chinensis). J Agric Food Chem. 2013;61:1943-53

[65]

Omary MB, Brovelli EA, Pusateri DJ et al. Sulforaphane potential and vitamin C concentration in developing heads and leaves of broccoli (Brassica oleracea var. italica). J Food Quality. 2003;26:523-30

[66]

Rangkadilok N, Nicolas ME, Bennett RN et al. Developmental changes of sinigrin and glucoraphanin in three Brassica species (Brassica nigra, Brassica juncea and Brassica oleracea var. italica). Sci Hortic. 2002;96:11-26

[67]

Gao C, Zhang F, Hu Y. et al. Dissecting the genetic architecture of glucosinolate compounds for quality improvement in flow-ering stalk tissues of Brassica napus. Hortic Plant J. 2023;9:553-62

[68]

Park WT, Kim JK, Park S. et al. Metabolic profiling of glucosino-lates, anthocyanins, carotenoids, and other secondary metabo-lites in kohlrabi (Brassica oleracea var. gongylodes). J Agric Food Chem. 2012;60:8111-6

[69]

Park CH, Yeo HJ, Park SY. et al. Comparative phytochemical anal-yses and metabolic profiling of different phenotypes of Chinese cabbage (Brassica Rapa ssp. Pekinensis). Food Secur. 2019;8:587

[70]

Keck AS, Finley JW. Cruciferous vegetables: cancer protective mechanisms of glucosinolate hydrolysis products and sele-nium. Integr Cancer Ther. 2004;3:5-12

[71]

Pennington JAT, Fisher RA. Food component profiles for fruit and vegetable subgroups. J Food Compost Anal. 2010;23:411-8

[72]

Kaulmann A, Jonville MC, Schneider YJ et al. Carotenoids, polyphenols and micronutrient profiles of Brassica oleraceae and plum varieties and their contribution to measures of total antioxidant capacity. Food Chem. 2014;155:240-50

[73]

Benzie IF. Evolution of dietary antioxidants. Comp Biochem Phys-iol A Mol Integr Physiol. 2003;136:113-26

[74]

Li Y, Schellhorn HE. Can ageing-related degenerative diseases be ameliorated through administration of vitamin C at phar-macological levels? Med Hypotheses. 2007;68:1315-7

[75]

Conrad ME, Schade SG. Ascorbic acid chelates in iron absorp-tion: a role for hydrochloric acid and bile. Gastroenterology. 1968;55:35-45

[76]

Chen Q, Espey MG, Krishna MC et al. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissue. P Natl Acad Sci USA. 2005;102:13604-9

[77]

Dennison BA, Rockwell HL, Baker SL. Fruit and vegetable intake in young children. J Am Coll Nutr. 1998;17:371-8

[78]

Domínguez-Perles R, Mena P, García-Viguera C et al. Brassica foods as a dietary source of vitamin C: a review. Crit Rev Food Sci Nutr. 2014;54:1076-91

[79]

Frei B, Lawson S. Vitamin C and cancer revisited. Proc Natl Acad Sci USA. 2008;105:11037-8

[80]

Moreno DA, Carvajal M, López-Berenguer C et al. Chemical and biological characterisation of nutraceutical compounds of broccoli. J Pharm Biomed Anal. 2006;41:1508-22

[81]

McKillop DJ, Pentieva K, Daly D. et al. The effect of different cooking methods on folate retention in various foods that are amongst the major contributors to folate intake in the UK diet. Brit J Nutr. 2002;88:681-8

[82]

Melse-Boonstra A, Verhoef P, Konings EJ et al. Influence of processing on total, monoglutamate and polyglutamate folate contents of leeks, cauliflower, and green beans. J Agric Food Chem. 2002;50:3473-8

[83]

Shohag M, Wei Y, Zhang J. et al. Genetic and physiological regulation of folate in pak choi (Brassica rapa subsp. Chinensis) germplasm. JExp Bot. 2020;71:4914-29

[84]

Farnham MW, Lester GE, Hassell R. Collard, mustard and turnip greens: effects of genotypes and leaf position on concentra-tions of ascorbic acid, folate, β-carotene, lutein and phylloqui-none. J Food Compos Anal. 2012;27:1-7

[85]

Bolton-Smith C, Price RJG, Fenton ST et al.Compilation of provisional UK database for the phylloquinone (vitamin K1) content of foods. Brit J Nutr. 2000;83:389-99

[86]

Ferland G, Sadowski JA. Vitamin K 1 (phylloquinone) content of green vegetables: effects of plant maturation and geographical growth location. J Agric Food Chem. 1992;40:1874-7

[87]

Basset GJ, Latimer S, Fatihi A. et al. Phylloquinone (vitamin K1): occurrence, biosynthesis and functions. Mini-Rev Med Chem. 2017;17:1028-38

[88]

Zou L, Tan WK, Du Y. et al. Nutritional metabolites in Brassica rapa subsp. chinensis var. parachinensis (choy sum) at three differ-ent growth stages: microgreen, seedling and adult plant. Food Chem. 2021;357:129535

[89]

Simes DC, Viegas CSB, Araújo N et al. VitaminKasadiet supplement with impact in human health: current evidence in age-related diseases. Nutrients. 2020;12:138

[90]

Schwartz H, Ollilainen V, Piironen V et al. Tocopherol, tocotrienol and plant sterol contents of vegetable oils and industrial fats. J Food Compos Anal. 2008;21:152-61

[91]

Guzman I, Yousef GG, Brown AF. Simultaneous extraction and quantitation of carotenoids, chlorophylls, and tocopherols in Brassica vegetables. J Agric Food Chem. 2012;60:7238-44

[92]

Michalak M. Plant-derived antioxidants: significance in skin health and the ageing process. Int J Mol Sci. 2022;23:585

[93]

Eggersdorfer M, Wyss A. Carotenoids in human nutrition and health. Arch Biochem Biophys. 2018;652:18-26

[94]

Maiani G, Periago Castón MJ, Catasta G et al. Carotenoids: actual knowledge on food sources, intakes, stability and bioavailabil-ity and their protective role in humans. Mol Nutr Food Res. 2009;53:S194-218

[95]

Mageney V, Baldermann S, Albach DC. Intraspecific variation in carotenoids of Brassica oleracea var. sabellica. J Agric Food Chem. 2016;64:3251-7

[96]

Lee S, Lee SC, Byun DH. et al. Association of molecular markers derived from the BrCRTISO1 gene with prolycopene-enriched orange-colored leaves in Brassica rapa [corrected]. Theor Appl Genet. 2014;127:179-91

[97]

Su T, Yu S, Zhang J. et al. Loss of function of the carotenoid isomerase gene BrCRTISO confers Orange color to the inner leaves of Chinese cabbage ( Brassica rapa L. ssp. pekinensis). Plant Mol Biol Report. 2015;33:648-59

[98]

Mrowicka M, Mrowicki J, Kucharska E et al. Lutein and Zeax-anthin and their roles in age-related macular degeneration-neurodegenerative disease. Nutrients. 2022;14:827

[99]

Nishino H, Murakosh M, Ii T. et al. Carotenoids in cancer chemo-prevention. Cancer Metastasis Rev. 2002;21:257-64

[100]

Martins T, Barros AN, Rosa E. et al. Enhancing health benefits through chlorophylls and chlorophyll-rich agro-food: a com-prehensive review. Molecules. 2023;28:5344

[101]

Mattioli R, Francioso A, Mosca L. et al. Anthocyanins: a compre-hensive review of their chemical properties and health effects on cardiovascular and neurodegenerative diseases. Molecules. 2020;25:3809

[102]

Różańska D, Regulska-Ilow B. The significance of anthocyanins in the prevention and treatment of type 2 diabetes. Adv Clin Exp Med. 2018;27:135-42

[103]

Zhao X, Feng P, He W. et al. The prevention and inhibition effect of anthocyanins on colorectal cancer. Curr Pharm Des. 2020;25:4919-27

[104]

Zhou Y, Zheng J, Li Y. et al. Natural polyphenols for prevention and treatment of cancer. Nutrients. 2016;8:515

[105]

Podsedek A. Natural antioxidants and antioxidant capacity of brassica vegetables: a review. Lwt-Food Sci Technol. 2007;40:1-11

[106]

Bahorun T, Luximon-Ramma A, Crozier A et al. Total phenol, flavonoid, proanthocyanidin and vitamin C levels and antiox-idant activities of Mauritian vegetables. J Sci Food Agr. 2004;84:1553-61

[107]

Yuan Y, Chiu LW, Li L. Transcriptional regulation of antho-cyanin biosynthesis in red cabbage. Planta. 2009;230:1141-53

[108]

Wang W, Zhang D, Yu S. et al. Mapping the BrPur gene for purple leaf color on linkage group A03 of Brassica rapa. Euphytica. 2014;199:293-302

[109]

Olsen H, Aaby K, Borge GI. Characterization, quantification, and yearly variation of the naturally occurring polyphenols in a common red variety of curly kale (Brassica oleracea L. convar. Acephala var. sabellica cv. ’Redbor’). J Agric Food Chem. 2010;58:11346-54

[110]

Jaiswal AK, Abu-Ghannam N, Gupta S. A comparative study on the polyphenolic content, antibacterial activity and antiox-idant capacity of different solvent extracts of Brassica oleracea vegetables. Int J Food Sci Technol. 2012;47:223-31

[111]

Prasad M, Joshi S, Narendra K et al. A comparative study of phy-tochemical analysis and in vitro antimicrobial activity of three important vegetables from brassicaceae family. International J Res Ayurveda Pharmacy. 2015;6:767-72

[112]

Heaney R, Weaver C, Hinders S et al. Absorbability of calcium from Brassica vegetables: broccoli, bok choy, and kale. J Food Sci. 1993;58:1378-80

[113]

Kamchan A, Puwastien P, Sirichakwal PP et al. In vitro calcium bioavailability of vegetables, legumes and seeds. J Food Compos Anal. 2004;17:311-20

[114]

Lucarini M, Canali R, Cappelloni M et al. In vitro cal-cium availability from brassica vegetables ( Brassica oleracea L.) and as consumed in composite dishes. Food Chem. 1999;64:519-23

[115]

Binia A, Jaeger J, Hu Y. et al. Daily potassium intake and sodium-to-potassium ratio in the reduction of blood pressure: a meta-analysis of randomized controlled trials. J Hypertens Suppl. 2015;33:1509-20

[116]

Satheesh N, Workneh FS. Kale: review on nutritional compo-sition, bio-active compounds, anti-nutritional factors, health beneficial properties and value-added products. Cogent Food Agr. 2020;6:1811048

[117]

Lefsrud M, Kopsell D, Wenzel A. et al. Changes in kale (Bras-sica oleracea L. var. acephala) carotenoid and chlorophyll pig-ment concentrations during leaf ontogeny. Sci Hortic. 2007;112:136-41

[118]

Duffield-Lillico AJ, Reid ME, Turnbull BW et al. Baseline charac-teristics and the effect of selenium supplementation on cancer incidence in a randomized clinical trial: a summary report of the nutritional prevention of cancer trial. Cancer Epidem Biomar. 2002;11:630-9

[119]

Irion CW. Growing alliums and brassicas in selenium-enriched soils increases their anticarcinogenic potentials. Med Hypothe-ses. 1999;53:232-5

[120]

Bañuelos GS. Irrigation of broccoli and canola with boron- and selenium-laden effluent. J Environ Qual. 2002;31:1802-8

[121]

Xiao Z, Lester GE, Luo Y. et al. Assessment of vitamin and carotenoid concentrations of emerging food products: edible microgreens. J Agric Food Chem. 2012;60:7644-51

[122]

Samec D, Salopek-Sondi B. Cruciferous (Brassicaceae) vegeta-bles. In: NabaviSM, SilvaAS, Nonvitaminand Nonmineral Nutritional Supplements. ElsevierInc.eds. Amsterdam, Netherlands. 2019,195-202

[123]

Hannoufa A, Pillai BV, Chellamma S. Genetic enhancement of Brassica napus seed quality. Transgenic Res. 2014;23:39-52

[124]

Yu B, Lydiate DJ, Young LW. et al. Enhancing the carotenoid content of Brassica napus seeds by downregulating lycopene epsilon cyclase. Transgenic Res. 2008;17:573-85

[125]

Vles RO, Bijster GM, Timmer WG. Nutritional Evaluation of Low-Erucic-Acid Rapeseed Oils. In: LeonardBJ, Toxicological Aspects of Food Safety. Springer Berlin Heidelberg.ed. New York, USA.1978,23-32

[126]

Cacciola F, Beccaria M, Oteri M. et al. Chemical characterization of old cabbage (Brassica oleracea L. var. acephala) seed oil by liquid chromatography and different spectroscopic detection systems. Nat Prod Res. 2016;30:1646-54

[127]

Murador DC, Mercadante AZ, de Rosso VV. Cooking techniques improve the levels of bioactive compounds and antioxidant activity in kale and red cabbage. Food Chem. 2016;196:1101-7

[128]

Diamante MS, Vanz Borges C, Minatel IO et al. Domestic cooking practices influence the carotenoid and tocopherol content in colored cauliflower. Food Chem. 2021;340:127901

[129]

Phan MAT, Bucknall MP, Arcot J. Effects on intestinal cellular bioaccessibility of carotenoids and cellular biological activ-ity as a consequence of co-ingestion of anthocyanin- and carotenoid-rich vegetables. Food Chem. 2019;286:678-85

[130]

Garber AK, Binkley NC, Krueger DC et al. Comparison of phyllo-quinone bioavailability from food sources or a supplement in human subjects. J Nutr. 1999;129:1201-3

[131]

Gupta E, Mishra P. Functional food with some health benefits, so called superfood: a review. Curr Nutr Food Sci. 2021;17:144-66

[132]

Šamec D, Urlić B, Salopek-Sondi B. Kale (Brassica oleracea var. acephala) as a superfood: review of the scientific evidence behind the statement. Crit Rev Food Sci Nutr. 2019;59:2411-22

[133]

Frede K, Baldermann S. Accumulation of carotenoids in Brassica rapa ssp. chinensis byahighproportionofblueinthe light spectrum. Photochem Photobiol Sci. 2022;21:1947-59

[134]

Baenas N, Moreno DA, García-Viguera C. Selecting sprouts of Brassicaceae for optimum phytochemical composition. J Agric Food Chem. 2012;60:11409-20

[135]

Vale A, Santos J, Brito N. et al. Light influence in the nutritional composition of Brassica oleracea sprouts. Food Chem. 2015;178:292-300

[136]

Carvalho SD, Folta KM. Sequential light programs shape kale (Brassica napus) sprout appearance and alter metabolic and nutrient content. Hortic Res. 2014;1:8

[137]

Hallmann E, Kazimierczak R, Marszałek K et al.The nutritive value of organic and conventional white cabbage (Brassica Oleracea L. Var. Capitata) and anti-apoptotic activity in gastric adenocarcinoma cells of sauerkraut juice produced Therof. J Agric Food Chem. 2017;65:8171-83

[138]

Kapusta-Duch J, Leszczyńska T, Filipiak-Florkiewicz A. Com-parison of total polyphenol contents and antioxidant activity in cruciferous vegetables grown in diversified ecological con-ditions. Acta Sci Polon-Techn. 2012;11:335-46

[139]

Geilfus CM, Hasler K, Witzel K. et al. Interactive effects of genotype and N/S-supply on glucosinolates and glucosinolate breakdown products in Chinese cabbage (Brassica rapa L. ssp. pekinensis). J Appl Bot Food Qual. 2016;89:279-86

[140]

Hu K, Zhu Z. Effects of different concentrations of sodium chloride on plant growth and glucosinolate content and com-position in pakchoi. Afr J Biotechnol. 2010;9:4428-33

[141]

Ilahy R, Tlili I, Pék Z et al. Pre-and post-harvest factors affecting glucosinolate content in broccoli. Front Nutr. 2020;7:147

[142]

Ferrari G, Renosto F. Regulation of sulfate uptake by excised barley roots in the presence of selenate. Plant Physiol. 1972;49:114-6

[143]

Mao S, Wang J, Wu Q. et al. Effect of selenium-sulfur interaction on the anabolism of sulforaphane in broccoli. Phytochemistry. 2020;179:112499

[144]

Kumar S, DePauw RM, Kumar S. et al. Breeding and adoption of biofortified crops and their nutritional impact on human health. Ann N Y Acad Sci. 2023;1520:5-19

[145]

Subramanian P, Kim SH, Hahn BS. Brassica biodiversity con-servation: prevailing constraints and future avenues for sus-tainable distribution of plant genetic resources. Front Plant Sci. 2023;14:1220134

[146]

Faulkner K, Mithen R, Williamson G. Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl glucosi-nolate in broccoli. Carcinogenesis. 1998;19:605-9

[147]

Broadley MR, Hammond JP, King GJ. et al. Biofortifying brassica with calcium (Ca) and magnesium (Mg). Proceed-ings of the International Plant Nutrition Colloquium XVI. 2009; 1256

[148]

Van Der Straeten D, Bhullar NK,De Steur H et al. Multiplying the efficiency and impact of biofortification through metabolic engineering. Nat Commun. 2020;11:5203

[149]

Tuncel A, Pan C, Sprink T. et al. Genome-edited foods. Nat Rev Bioeng. 2023;1:799-816

[150]

Cheng F, Mandáková T, Wu J. et al. Deciphering the diploid ancestral genome of the Mesohexaploid Brassica rapa. Plant Cell. 2013;25:1541-54

[151]

Miao H, Zeng W, Wang J. et al. Improvement of glucosinolates by metabolic engineering in Brassica crops. aBIOTECH. 2021;2:314-29

[152]

Yang Y, Hu Y, Yue Y. et al. Expression profiles of glucosinolate biosynthetic genes in turnip (Brassica rapa var. rapa) at differ-ent developmental stages and effect of transformed flavin-containing monooxygenase genes on hairy root glucosinolate content. J Sci Food Agric. 2020;100:1064-71

[153]

Bai X, Zhang R, Zeng Q. et al. The RNA-binding protein BoRHON1 positively regulates the accumulation of aliphatic Glucosino-lates in cabbage. Int J Mol Sci. 2024;25:5314

[154]

Wu Q, Mao S, Huang H. et al. Chromosome-scale refer-ence genome of broccoli (Brassica oleracea var. italica Plenck) provides insights into glucosinolate biosynthesis. Hortic Res. 2024;11:uhae063

[155]

Cai C, de Vos RCH, Qian H. et al. Metabolomic and transcriptomic profiles in diverse Brassica oleracea crops provide insights into the genetic regulation of Glucosinolate profiles. J Agric Food Chem. 2024;72:16032-44

[156]

Augustine R, Bisht NC. Biofortification of oilseed Brassica juncea with the anti-cancer compound glucoraphanin by suppressing gsl-alk gene family. Sci Rep-UK. 2016;5:18005

[157]

Liu Z, Hirani AH, McVetty PBE et al. Reducing progoitrin and enriching glucoraphanin in Brassica napus seeds through silenc-ing of the gsl-alk gene family. Plant Mol Biol. 2012;79:179-89

[158]

Liu Z, Liang J, Zheng S. et al. Enriching glucoraphanin in Bras-sica rapa through replacement of BrAOP2.2/BrAOP2.3 with non-functional genes. Front Plant Sci. 2017;8:1329

[159]

Tuan PA, Kim JK, Lee J. et al. Analysis of carotenoid accumulation and expression of carotenoid biosynthesis genes in different organs of Chinese cabbage (Brassica rapa subsp. pekinensis). EXCLI J. 2012;11:508-16

[160]

Li L, Paolillo DJ, Parthasarathy MV et al. A novel gene mutation that confers abnormal patterns of beta-carotene accumulation in cauliflower (Brassica oleracea var. botrytis). Plant J. 2001;26:59-67

[161]

Zhou X, Van Eck J, Li L. Use of the cauliflower or gene for improving crop nutritional quality. Biotechnol Annu Rev. 2008;14:171-90

[162]

Feng H, Li Y, Liu Z. et al. Mapping of or, a gene conferring orange color on the inner leaf of the Chinese cabbage (Brassica rapa L. ssp. pekinensis). Mol Breeding. 2012;29:235-44

[163]

Zhang J, Li H, Zhang M. et al. Fine mapping and identification of candidate Br-or gene controlling orange head of Chinese cabbage (Brassica rapa L. ssp. pekinensis). Mol Breeding. 2013;32:799-805

[164]

Su T, Wang W, Li P. et al. Natural variations of BrHISN2 provide a genetic basis for growth-flavour trade-off in different Brassica rapa subspecies. New Phytol. 2021;231:2186-99

[165]

Li P, Lv S, Zhang D. et al. The carotenoid esterification gene BrPYP controls pale-yellow petal color in flowering Chinese cabbage (Brassica rapa L. subsp. parachinensis). Front Plant Sci. 2022;13:844140

[166]

Ren Y, Han R, Ma Y. et al. Transcriptomics integrated with metabolomics unveil carotenoids accumulation and correlated gene regulation in white and yellow-fleshed turnip (Brassica rapa ssp. rapa). Genes (Basel). 2022;13:953

[167]

He Q, Zhang Z, Zhang L. Anthocyanin accumulation, antiox-idant ability and stability, and a transcriptional analysis of anthocyanin biosynthesis in purple heading Chinese cabbage (Brassica rapa L. ssp. pekinensis). J Agric Food Chem. 2016;64:132-45

[168]

Heng S, Cheng Q, Zhang T. et al. Fine-mapping of the BjPur gene for purple leaf color in Brassica juncea. Theor Appl Genet. 2020;133:2989-3000

[169]

Li X, Gao MJ, Pan HY. et al. Purple canola: Arabidopsis PAP1 increases antioxidants and phenolics in Brassica napus leaves. J Agric Food Chem. 2010;58:1639-45

[170]

Li H, Zhu L, Yuan G. et al. Fine mapping and candidate gene analysis of an anthocyanin-rich gene, BnaA.PL1, conferring purple leaves in Brassica napus L. Mol Gen Genomics. 2016;291:1523-34

[171]

Goswami G, Nath UK, Park JI. et al. Transcriptional regulation of anthocyanin biosynthesis in a high-anthocyanin resynthesized Brassica napus cultivar. J Biol Res-Thessalon. 2018;25:19

[172]

Chen D, Liu Y, Yin S. et al. Alternatively spliced BnaPAP2.A 7 isoforms play opposing roles in anthocyanin biosynthesis of Brassica napus L. Front Plant Sci. 2020;11:983

[173]

Chiu LW, Zhou X, Burke S. et al. The purple cauliflower arises from activation of a MYB transcription factor. Plant Physiol. 2010;154:1470-80

[174]

Fu H, Chao H, Zhao X. et al. Anthocyanins identification and transcriptional regulation of anthocyanin biosynthesis in pur-ple Brassica napus. Plant Mol Biol. 2022;110:53-68

[175]

Schilbert HM, Schöne M, Baier T. et al. Characterization of the Brassica napus Flavonol synthase gene family reveals Bifunc-tional Flavonol synthases. Front Plant Sci. 2021;12:733762

[176]

Wang N, Shi L, Tian F. et al. Assessment of FAE 1 polymorphisms in three brassica species using EcoTILLING and their association with differences in seed erucic acid contents. BMC Plant Biol. 2010;10:137

[177]

Jiang M, Zhan Z, Li H. et al. Brassica rapa orphan genes largely affect soluble sugar metabolism. Hortic Res. 2020;7:181

[178]

Zhang Y, Hu Z, Zhu M. et al. Anthocyanin accumulation and molecular analysis of correlated genes in purple kohlrabi (Bras-sica oleracea var. gongylodes L.). J Agric Food Chem. 2015b;63:4160-9

[179]

Zhang J, Yuan H, Fei Z. et al. Molecular characterization and transcriptome analysis of orange head Chinese cabbage (Bras-sica rapa L. ssp. pekinensis). Planta. 2015a;241:1381-94

[180]

Osorio CE. The role of Orange gene in carotenoid accumulation: manipulating Chromoplasts toward a colored future. Front Plant Sci. 2019;10:1235

[181]

Pietta PG. Flavonoids as antioxidants. J Nat Prod. 2000;63:1035-42.

[182]

Raskin I, Ripoll C. Can an apple a day keep the doctor away? Curr Pharm Design. 2004;10:3419-29

[183]

Karniel U, Koch A, Zamir D. et al. Development of zeaxanthin-rich tomato fruit through genetic manipulations of carotenoid biosynthesis. Plant Biotechnol J. 2020;18:2292-303

[184]

Menconi J, Perata P, Gonzali S. In pursuit of purple: anthocyanin biosynthesis in fruits of the tomato clade. Trends Plant Sci. 2024;29:589-604

[185]

Li X, Kim YB, Uddin MR. et al. Influence of light on the free amino acid content and γ-aminobutyric acid synthe-sis in Brassica juncea seedlings. J Agric Food Chem. 2013;61:8624-31

[186]

Siucinska E. Γ-aminobutyric acid in adult brain: an update. Behav Brain Res. 2019;376:112224

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