We are excited to inform you that we have launched Special Issue: Brain-Computer Interface. Hoping that your high-quality research outcomes will help us build Human Brain into benchmarks in the field.

In recent years, the rapid evolution of brain‑computer interface (BCI) research has led to transformative advances in decoding neural activity and translating it into actionable control signals, with profound implications for neurorehabilitation, assistive communication and cognitive monitoring in both research and clinical contexts. This special topic seeks to bring together high‑impact contributions that address fundamental theoretical insights, methodological innovations, and translational frameworks that collectively advance the science and engineering of BCI systems. Topics of interest include, but are not limited to: novel machine learning and signal processing approaches for neural decoding and representation learning; algorithmic strategies for cross‑individual and cross‑task generalization; principled integration of multimodal electrophysiological and behavioral data for cognitive state analysis; design and evaluation of closed‑loop, low‑latency, and adaptive BCI systems; next‑generation hardware and wearable interface technologies; and rigorous empirical studies assessing clinical efficacy, usability, and long‑term outcomes. We welcome both original research articles and comprehensive reviews that bridge basic neuroscience, computational modeling, engineering innovation, and clinical translation.

Welcome manuscripts focusing on (not limited to)：

Neural signal decoding

Real‑time interaction and closed‑loop control

Multimodal integration and cognitive state analysis

Clinical and rehabilitation applications

Brain data security analysis and interpretability frameworks

Embedded and wearable systems

 

Submission deadline: 2026-12-30

 

Guest Editor

       

Yuanli Zhao

MD

Professor and director of Department of Neurosurgery, Peking Union Medical College Hospital, China

  

Wanru Duan

MD

Professor of Department of Neurosurgery, Xuanwu Hospital Capital Medical University, China