romoting stem cells activity using Chinese medicine herbs in treatment of neurological disorder: A review on novel therapeutic approaches

Abstract

Stem cell therapy represents a burgeoning and swiftly advancing modality for the treatment of a diverse array of neurological disorders. However, despite continued clinical trials, the underlying mechanisms of action often remain elusive. Traditional Chinese medicine (TCM), with its holistic approach, provides a valuable resource for the identification and evaluation of potential neuroprotective agents. Research has shown that TCM, including herbs, herbal extracts, and specific Chinese herbal constituents, can modulate the proliferation and differentiation of neural stem cells (NSCs) to some extent. This review examines the potential of TCM as a treatment for neurodegenerative diseases. Given the limitations of current therapies due to a lack of understanding of disease pathogenesis, a holistic approach to TCM offers a promising alternative. This paper also summarizes the role of stem cells in the management of neurological disorders and evaluates prior studies concerning stem cell transplantation. In addition, it explores the capacity of TCM to influence the proliferation and differentiation of NSCs. The ultimate aim of this review is to enhance our understanding of how TCM can be utilized to influence stem cell behavior and potentially treat neurodegenerative diseases.

Keywords

Stem cell / Traditional Chinese medicine / Neurodegenerative diseases / Neuroprotective agents

Funding

None.

Conflict of interest

The authors declare that they have no competing interests.

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