Impact of outbreaks caused by respiratory viruses on healthcare and economic systems: A systematic review
Kathleen Carvalho , Mihajlo Jakovljevic , Luis Paulo Reis , João Paulo Teixeira
Global Health Economics and Sustainability ›› 2026, Vol. 4 ›› Issue (1) : 34 -48.
A pandemic’s socioeconomic disruption can result in deaths due to deprivation, suicide, violence, and trauma, in addition to virus-related consequences. This study seeks to map the scientific literature on the effects of mitigation measures for respiratory virus outbreaks on healthcare and economic systems across countries, as well as the models used to predict those effects. The primary objectives were to identify the main contributions in this field and delineate the major research pathways that can inform a future research agenda. The study uses bibliometric analysis, keyword co-occurrence analysis, and cluster analysis. Keyword linkages were examined to identify possible trends across the retrieved papers. Hierarchical cluster analysis was also applied to categorize related papers into distinct groups. The results facilitated the identification and classification of multiple theoretical perspectives derived from primary research across seven major approaches: (i) economic parameters affected by the COVID-19 crisis; (ii) healthcare crisis management; (iii) predictions of government interventions’ impact on the healthcare system; (iv) impacts of influenza virus in a global economic scenario; (v) general impacts of outbreaks in European and Asia Pacific countries; (vi) operating statistical stability in data analysis; and (vii) statistical trends regarding healthcare in a global economy over a pandemic crisis. Overall, the review synthesizes the main themes in the literature and highlights priority areas related to economic systems, healthcare systems, and predictive modeling. The findings highlight the strong interconnections among economic stability, healthcare system resilience, and public policy, while identifying key health and economic parameters that may inform predictive models assessing the effects of mitigation measures.
Bibliometrics / Healthcare system / Economic system / Pandemic’s socioeconomic disruption / COVID-19 / SARS-CoV-2
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