Hopf bifurcation of a tumor immune model with time delay

Yanhong YANG , Shengmao FU

Front. Math. China ›› 2022, Vol. 17 ›› Issue (2) : 315 -335.

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Front. Math. China ›› 2022, Vol. 17 ›› Issue (2) : 315 -335. DOI: 10.1007/s11464-022-1013-2
RESEARCH ARTICLE
RESEARCH ARTICLE

Hopf bifurcation of a tumor immune model with time delay

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Abstract

In this paper, a tumor immune model with time delay is studied. First, the stability of nonnegative equilibria is analyzed. Then the time delay τ is selected as a bifurcation parameter and the existence of Hopf bifurcation is proved. Finally, by using the canonical method and the central manifold theory, the criteria for judging the direction and stability of Hopf bifurcation are given.

Keywords

Tumor immune model / time delay / Hopf bifurcation / existence / direction / stability

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Yanhong YANG, Shengmao FU. Hopf bifurcation of a tumor immune model with time delay. Front. Math. China, 2022, 17(2): 315-335 DOI:10.1007/s11464-022-1013-2

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