Global Integration of Traditional and Modern Medicine: Policy Developments, Regulatory Frameworks, and Clinical Integration Model

Gangadharan Thamizhoviya

›› 2025, Vol. 4 ›› Issue (3) : 180 -190.

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›› 2025, Vol. 4 ›› Issue (3) : 180 -190. DOI: 10.14218/FIM.2025.00033
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Global Integration of Traditional and Modern Medicine: Policy Developments, Regulatory Frameworks, and Clinical Integration Model

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Abstract

Globally, the integration of traditional medicine and modern medicine has been recognized as a global health priority aimed at improving healthcare accessibility, cultural relevance, and therapeutic effectiveness. This review systematically examines the global landscape of traditional medicine-modern medicine integration by analyzing policy developments, regulatory frameworks, and clinical implementation models across various regions, including Asia, Africa, Europe, and the USA. The scope of the review encompasses five key domains: (1) global policy initiatives, (2) regulatory and institutional frameworks, (3) clinical integration models, (4) impacts and outcomes of integrative practices, and (5) challenges and barriers to implementation. Based on peer-reviewed literature and official health policy documents published between 2000 and 2025, the present review investigates how countries have operationalized clinical integration models combining traditional and complementary medicine. Although interest in traditional and complementary medicine has grown worldwide, persistent challenges, such as limited scientific validation, lack of standardization, and professional resistance, continue to hinder progress. This review concludes that successful and sustainable integration requires evidence-based clinical approaches, inclusive regulatory reforms, and coordinated policy strategies. Countries such as China, India, and Brazil have made significant advances, offering valuable models for future implementation worldwide.

Keywords

Traditional medicine integration / Health policy / Regulatory frameworks / Clinical integration models / Modern medicine / Traditional and complementary medicine

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Gangadharan Thamizhoviya. Global Integration of Traditional and Modern Medicine: Policy Developments, Regulatory Frameworks, and Clinical Integration Model. , 2025, 4(3): 180-190 DOI:10.14218/FIM.2025.00033

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References

[1]

Zhang Q. Traditional and complementary medicine in primary health care. In: MedcalfA, BhattacharyaS, MomenH, SaavedraM, Jones M (eds). Health For All:The Journey of Universal Health Coverage. Hyderabad (IN): Orient Blackswan; 2015.

[2]

Patwardhan B, Warude D, Pushpangadan P, Bhatt N. Ayurveda and traditional Chinese medicine: a comparative overview. Evid Based Complement Alternat Med 2005; 2(4):465-473. doi:10.1093/ecam/ neh140, PMID:16322803.

[3]

Firenzuoli F, Gori L. European traditional medicine - international congress - introductory statement. Evid Based Complement Alternat Med 2007; 4(Suppl 1):3-4. doi:10.1093/ecam/nem134, PMID:18227922.

[4]

Jaiswal YS, Williams LL. A glimpse of Ayurveda - The forgotten history and principles of Indian traditional medicine. J Tradit Complement Med 2017; 7(1):50-53. doi:10.1016/j.jtcme.2016.02.002, PMID:28053888.

[5]

Hoenders R, Ghelman R, Portella C, Simmons S, Locke A, Cramer H, et al. A review of the WHO strategy on traditional, complementary, and integrative medicine from the perspective of academic consortia for integrative medicine and health. Front Med (Lausanne) 2024;11:1395698. doi:10.3389/fmed.2024.1395698, PMID:38933107.

[6]

Jain T, Dubey D, Jain V, Dashora K. Regulatory status of traditional medicines in different countries: An overview. Research J Pharm and Tech 2011; 4(7):1007-1015.

[7]

von Schoen-Angerer T, Manchanda RK, Lloyd I, Wardle J, Szöke J, Benevides I, et al. Traditional, complementary and integrative healthcare: global stakeholder perspective on WHO’s current and future strategy. BMJ Glob Health 2023; 8(12):e013150. doi:10.1136/ bmjgh-2023-013150, PMID:38050407.

[8]

Vaidya AD, Devasagayam TP. Current status of herbal drugs in India: an overview. J Clin Biochem Nutr 2007; 41(1):1-11. doi:10.3164/ jcbn.2007001, PMID:18392106.

[9]

Milenkovic J, Bolevich S, Rosic G. Complementary and alternative medicine in European countries-legislative framework. Traditional Medicine Research 2020; 5(3):125. doi:10.53388/TMR20190718125.

[10]

Burton A, Smith M, Falkenberg T. Building WHO’s global strategy for traditional medicine. European Journal of Integrative Medicine 2015; 7(1):13-15. doi:10.1016/j.eujim.2014.12.007.

[11]

World Health Organization.WHO global report on traditional and complementary medicine 2019. Geneva, Switzerland: World Health Organization; 2019.

[12]

Zhang X. Integration of traditional and complementary medicine into national health care systems. J Manipulative Physiol Ther 2000;23(2):139-140. doi:10.1016/s0161-4754(00)90085-x, PMID:107 14545.

[13]

Habib SH, Saha S. Burden of non-communicable disease: global overview. Diabetes Metab Syndr Clin Res Rev 2010; 4(1):41-47. doi: 10.1016/j.dsx.2008.04.005.

[14]

Dew K, Liyanagunawardena S. Traditional medicine and global public health. In: LiamputtongP ed. Handbook of Social Sciences and Global Public Health. Cham: Springer International Publishing; 2023:221-237. doi:10.1007/978-3-031-25110-8_16.

[15]

Rizvi SAA, Einstein GP, Tulp OL, Sainvil F, Branly R. Introduction to Traditional Medicine and Their Role in Prevention and Treatment of Emerging and Re-Emerging Diseases. Biomolecules 2022; 12(10):1442. doi:10.3390/biom12101442, PMID:36291651.

[16]

Street R, Falkenberg T, Sundberg T, Balakrishna Y, Abrams A, Kredo T. Participation of traditional, complementary and alternative health practitioners in conventional health systems in low- and middleincome countries. Cochrane Database Syst Rev 2019;8:CD013391. doi:10.1002/14651858.CD013391.

[17]

Maikhuri RK, Maletha A, Singh R, Bhatt G, Agarwal S, Dhyani S, et al. Traditional health care systems and immunity boosting: exploring plant based indigenous knowledge systems amidst the COVID-19 pandemic. Discov Plants 2024; 1(1):5. doi:10.1007/s44372-024-00005-2.

[18]

Avilés-Polanco G, Jefferson DJ, Almendarez-Hernández MA, Beltrán- Morales LF. Factors that explain the utilization of the Nagoya protocol framework for access and benefit sharing. Sustainability 2019; 11(20):5550. doi:10.3390/su11205550.

[19]

Leonti M, Casu L. Traditional medicines and globalization: current and future perspectives in ethnopharmacology. Front Pharmacol 2013;4:92. doi:10.3389/fphar.2013.0009, PMID:23898296.

[20]

Chung VCH, Wong CHL, Zhong CCW, Tjioe YY, Leung TH, Griffiths SM. Traditional and complementary medicine for promoting healthy ageing in WHO Western Pacific Region: Policy implications from utilization patterns and current evidence. Integr Med Res 2021; 10(1):100469. doi:10.1016/j.imr.2020.100469, PMID:32874912.

[21]

van der Greef J, van Wietmarschen H, Schroën Y, Babouraj N, Trousselard M. Systematic approaches to evaluation and integration of eastern and Western medical practices. Medical Acupuncture 2015; 27(5):384-395. doi:10.1089/acu.2015.1123.

[22]

World Health Organization. WHO Traditional Medicine Strategy: 2014-2023. Geneva: World Health Organization; 2013.

[23]

Rudra S, Kalra A, Kumar A, Joe W. Utilization of alternative systems of medicine as health care services in India: Evidence on AYUSH care from NSS 2014. PLoS One 2017; 12(5):e0176916. doi:10.1371/journal. pone.0176916, PMID:28472197.

[24]

Wang L, Wang Z, Ma Q, Fang G, Yang J. The development and reform of public health in China from 1949 to 2019. Global Health 2019; 15(1):45. doi:10.1186/s12992-019-0486-6, PMID:31266514.

[25]

Watanabe K, Matsuura K, Gao P, Hottenbacher L, Tokunaga H, Nishimura K, et al. Traditional Japanese Kampo Medicine: Clinical Research between Modernity and Traditional Medicine-The State of Research and Methodological Suggestions for the Future. Evid Based Complement Alternat Med 2011; 2011:513842. doi:10.1093/ecam/ neq067, PMID:21687585.

[26]

Park JS, Shin BC, Kim CB, Jeong TY, Lee YW, Cho CK, et al. A policy proposal for the Korean collaboration of Eastern and Western medicine according to a model of the Chinese integrative medicine. J Haehwa Med 2010; 19(1):1-7.

[27]

World Health Organization. WHO country stories: delivering for all. Geneva: World Health Organization; 2023.

[28]

Joos S, Musselmann B, Szecsenyi J. Integration of complementary and alternative medicine into family practices in Germany: results of a national survey. Evid Based Complement Alternat Med 2011; 2011:495813. doi:10.1093/ecam/nep019, PMID:19293252.

[29]

Garcia-Cerde R, de Medeiros PFP, Silva LF, Valente JY, Andreoni S, Sanchez ZM, et al. Use of integrative and complementary health practices by Brazilian population: results from the 2019 National Health Survey. BMC Public Health 2023; 23(1):1153. doi:10.1186/ s12889-023-16083-y, PMID:37316825.

[30]

Nahin RL, Rhee A, Stussman B. Use of Complementary Health Approaches Overall and for Pain Management by US Adults. JAMA 2024; 331(7):613-615. doi:10.1001/jama.2023.26775, PMID:38270938.

[31]

Zhang X. Regulatory Situation of Herbal Medicines A worldwide Review. Geneva: World Health Organization; 1998.

[32]

Shankar D, Patwardhan B. AYUSH for New India: Vision and strategy. J Ayurveda Integr Med 2017; 8(3):137-139. doi:10.1016/j. jaim.2017.09.001, PMID:28923183.

[33]

Hu Q. The regulation of Chinese medicine in China. Longhua Chin Med 2021; 4:7. doi:10.21037/lcm-2021-001.

[34]

Kim D, Shih CC, Cheng HC, Kwon SH, Kim H, Lim B. A comparative study of the traditional medicine systems of South Korea and Taiwan: Focus on administration, education and license. Integr Med Res 2021; 10(3):100685. doi:10.1016/j.imr.2020.100685, PMID:33665088.

[35]

Krug K, Kraus KI, Herrmann K, Joos S. Complementary and alternative medicine (CAM) as part of primary health care in Germanycomparison of patients consulting general practitioners and CAM practitioners: a cross-sectional study. BMC Complement Altern Med 2016; 16(1):409. doi:10.1186/s12906-016-1402-8, PMID:27776512.

[36]

Habimorad PHL, Catarucci FM, Bruno VHT, Silva IBD, Fernandes VC, Demarzo MMP, et al. Implementation of Brazil’s National Policy on Complementary and Integrative Practices: strengths and weaknesses. Cien Saude Colet 2020; 25(2):395-405. doi:10.1590/1413- 81232020252.11332018, PMID:32022181.

[37]

Steel A, McIntyre E, Harnett J, Foley H, Adams J, Sibbritt D, et al. Complementary medicine use in the Australian population: Results of a nationally-representative cross-sectional survey. Sci Rep 2018; 8(1):17325. doi:10.1038/s41598-018-35508-y, PMID:30470778.

[38]

Dwyer JT, Coates PM, Smith MJ. Dietary Supplements: Regulatory Challenges and Research Resources. Nutrients 2018; 10(1):41. doi:10.3390/nu10010041, PMID:29300341.

[39]

Patwardhan K, Gehlot S, Singh G, Rathore HC. Global challenges of graduate level Ayurvedic education: A survey. Int J Ayurveda Res 2010; 1(1):49-54. doi:10.4103/0974-7788.59945, PMID:20532099.

[40]

Singer J, Adams J. Integrating complementary and alternative medicine into mainstream healthcare services: the perspectives of health service managers. BMC Complement Altern Med 2014; 14:167. doi:10.1186/1472-6882-14-167, PMID:24885066.

[41]

Wang WJ, Zhang T. Integration of traditional Chinese medicine and Western medicine in the era of precision medicine. J Integr Med 2017;15(1):1-7. doi:10.1016/S2095-4964(17)60314-5, PMID:28088253.

[42]

Clarke TC, Black LI, Stussman BJ, Barnes PM, Nahin RL. Trends in the use of complementary health approaches among adults: United States, 2002-2012. Natl Health Stat Report 2015; 10(79):1-16. PMID:25671660.

[43]

Lim B. Korean medicine coverage in the National Health Insurance in Korea: present situation and critical issues. Integr Med Res 2013; 2(3):81-88. doi:10.1016/j.imr.2013.06.004, PMID:28664058.

[44]

Chen KJ, Xu H. The integration of traditional Chinese medicine and Western medicine. European Review 2003; 11(2):225-235. doi:10.1017/S106279870300022X.

[45]

Mwaka AD, Abbo C, Kinengyere AA. Traditional and Complementary Medicine Use Among Adult Cancer Patients Undergoing Conventional Treatment in Sub-Saharan Africa: A Scoping Review on the Use, Safety and Risks. Cancer Manag Res 2020; 12:3699-3712. doi:10.2147/CMAR.S251975, PMID:32547206.

[46]

Balachandran P, Govindarajan R. Cancer—an ayurvedic perspective. Pharmacol Res 2005; 51(1):19-30. doi:10.1016/j.phrs.2004.04.010, PMID:15519531.

[47]

Singh N, Bhalla M, de Jager P, Gilca M. An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda. Afr J Tradit Complement Altern Med 2011; 8(5 Suppl):208-213. doi:10.4314/ajtcam.v8i5S.9, PMID:22754076.

[48]

Shukla SS, Saraf S, Saraf S. Fundamental aspect and basic concept of siddha medicines. Syst Rev Pharm 2011; 2(1):48-54. doi:10.4103/0975-8453.83439.

[49]

Gangadharan T, Arumugam M. Siddha medicine and modern neuroscience: a synergistic approach to neurological care. 3 Biotech 2025; 15(4):96. doi:10.1007/s13205-025-04265-x, PMID:40124133.

[50]

Bell IR, Koithan M. A model for homeopathic remedy effects: low dose nanoparticles, allostatic cross-adaptation, and time-dependent sensitization in a complex adaptive system. BMC Complement Altern Med 2012; 12:191. doi:10.1186/1472-6882-12-191, PMID:23088629.

[51]

Mathie RT, Clausen J. Veterinary homeopathy: systematic review of medical conditions studied by randomised trials controlled by other than placebo. BMC Vet Res 2015; 11:236. doi:10.1186/s12917-015- 0542-2, PMID:26371366.

[52]

Field T. Yoga clinical research review. Complement Ther Clin Pract 2011; 17(1):1-8. doi:10.1016/j.ctcp.2010.09.007, PMID:21168106.

[53]

Streeter CC, Gerbarg PL, Saper RB, Ciraulo DA, Brown RP. Effects of yoga on the autonomic nervous system, gamma-aminobutyric-acid, and allostasis in epilepsy, depression, and post-traumatic stress disorder. Med Hypotheses 2012; 78(5):571-579. doi:10.1016/j. mehy.2012.01.021, PMID:22365651.

[54]

Ahmad A, Husain A, Mujeeb M, Khan SA, Najmi AK, Siddique NA, et al. A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pac J Trop Biomed 2013;3(5):337-352. doi:10.1016/S2221- 1691(13)60075-1, PMID:23646296.

[55]

Ansari S, Khan QA, Anjum R, Siddiqui A, Sultana K. Fundamentals of Unani system of medicine-a review. European Journal of Biomedical and Pharmaceutical Science 2017; 4(9):219-223.

[56]

Vickers AJ, Cronin AM, Maschino AC, Lewith G, MacPherson H, Foster NE, et al. Acupuncture for chronic pain: individual patient data metaanalysis. Arch Intern Med 2012; 172(19):1444-1453. doi:10.1001/ archinternmed.2012.3654, PMID:22965186.

[57]

Han JS. Acupuncture and endorphins. Neurosci Lett 2004; 361(1- 3):258-261. doi:10.1016/j.neulet.2003.12.019, PMID:15135942.

[58]

Huang M, Liu YY, Xiong K, Yang FW, Jin XY, Wang ZQ, et al. The role and advantage of traditional Chinese medicine in the prevention and treatment of COVID-19. J Integr Med 2023; 21(5):407-412. doi:10.1016/j.joim.2023.08.003, PMID:37625946.

[59]

Park J, Yi E, Yi J. The Provision and Utilization of Traditional Korean Medicine in South Korea: Implications on Integration of Traditional Medicine in a Developed Country. Healthcare (Basel) 2021; 9(10):1379. doi:10.3390/healthcare9101379, PMID:34683059.

[60]

Cha WS, Oh JH, Park HJ, Ahn SW, Hong SY, Kim NI. Historical difference between traditional Korean medicine and traditional Chinese medicine. Neurol Res 2007; 29(Suppl 1):S5-S9. doi:10.1179/0161641 07X172293, PMID:17359633.

[61]

Arai I. Clinical studies of traditional Japanese herbal medicines (Kampo): Need for evidence by the modern scientific methodology. Integr Med Res 2021; 10(3):100722. doi:10.1016/j.imr.2021.100722, PMID:34136346.

[62]

Abdullahi AA. Trends and challenges of traditional medicine in Africa. Afr J Tradit Complement Altern Med 2011; 8(5 Suppl):115-123. doi:10.4314/ajtcam.v8i5S.5, PMID:22754064.

[63]

Kofi-Tsekpo M. Institutionalization of African traditional medicine in health care systems in Africa. Afr J Health Sci 2004; 11(1-2): i-ii. doi:10.4314/ajhs.v11i1.30772, PMID:17298111.

[64]

Joos S, Glassen K, Musselmann B. Herbal Medicine in Primary Healthcare in Germany: The Patient’s Perspective. Evid Based Complement Alternat Med 2012; 2012:294638. doi:10.1155/2012/294638, PMID:23346197.

[65]

Welz AN, Emberger-Klein A, Menrad K. The importance of herbal medicine use in the German health-care system: prevalence, usage pattern, and influencing factors. BMC Health Serv Res 2019; 19(1):952. doi:10.1186/s12913-019-4739-0, PMID:31823758.

[66]

Bent S, Ko R. Commonly used herbal medicines in the United States: a review. Am J Med 2004; 116(7):478-485. doi:10.1016/j.amjmed. 2003.10.036, PMID:15047038.

[67]

Smith CL, Reddy B, Wolf CM, Schnyer RN, St John K, Conboy L, et al. The State of 21st Century Acupuncture in the United States. J Pain Res 2024; 17:3329-3354. doi:10.2147/JPR.S469491, PMID:39403098.

[68]

Russell R, Updyke WF, Green BN. History, Present and Prospect of Chiropractic. In: Shen Y (ed). History, Present and Prospect of World Traditional Medicine. Hackensack, NJ: World Scientific Publishing; 2024:73-130. doi:10.1142/9789811282171_0002.

[69]

de Sousa IMC, Benjamin Bezerra AF, Guimarães MB, de Almeida Benevides I, Tesser CD. Traditional, complementary and integrative medicine in the Brazilian public health service: opportunities and limitations. In: Adams J (ed). Public Health and Health Services Research in Traditional, Complementary and Integrative Health Care: International Perspectives. Hackensack, NJ: World Scientific Publishing; 2019:197-216. doi:10.1142/9781786346797_0012.

[70]

Bhuyan DJ, Dissanayake IH, Jaye K, Chang D. Traditional and complementary medicine in Australia: clinical practice, research, education, and regulation. International Journal of Ayurveda Research 2022; 3(1):16-29. doi:10.4103/ijar.ijar_4_22.

[71]

Ng JY, Cramer H, Lee MS, Moher D. Traditional, complementary, and integrative medicine and artificial intelligence: Novel opportunities in healthcare. Integr Med Res 2024; 13(1):101024. doi:10.1016/j. imr.2024.101024, PMID:38384497.

[72]

Nanda S. Integrating Traditional and Contemporary Systems for Health and Well-being. Ann Neurosci 2023; 30(2):77-78. doi:10.1177/ 09727531231185648, PMID:37706097.

[73]

Park YL, Canaway R. Integrating Traditional and Complementary Medicine with National Healthcare Systems for Universal Health Coverage in Asia and the Western Pacific. Health Syst Reform 2019; 5(1):24-31. doi:10.1080/23288604.2018.1539058, PMID:30924749.

[74]

Jasemi M, Valizadeh L, Zamanzadeh V, Keogh B. A Concept Analysis of Holistic Care by Hybrid Model. Indian J Palliat Care 2017; 23(1):71-80. doi:10.4103/0973-1075.197960, PMID:28216867.

[75]

Scott R, Nahin RL, Weber W. Longitudinal Analysis of Complementary Health Approaches in Adults Aged 25-74 Years from the Midlife in the U.S. Survey Sample. J Altern Complement Med 2021; 27(7):550-568. doi:10.1089/acm.2020.0414, PMID:33877882.

[76]

Knopf K. The turn toward the indigenous: Knowledge systems and practices in the academy. Amerikastudien/American Studies 2015; 60(2/3):179-200.

[77]

Hone T, Macinko J, Trajman A, Palladino R, Coeli CM, Saraceni V, et al. Expansion of primary healthcare and emergency hospital admissions among the urban poor in Rio de Janeiro, Brazil: a cohort analysis. Lancet Reg Health Am 2022;15:100363. doi:10.1016/j. lana.2022.100363, PMID:36778075.

[78]

Patwardhan B. Bridging Ayurveda with evidence-based scientific approaches in medicine. EPMA J 2014; 5(1):19. doi:10.1186/1878-5085- 5-19, PMID:25395997.

[79]

Bodeker G, Ong CK, Grundy C, Burford G, Shein K. Complementary and Alternative Medicine. WHO Global Atlas of Traditional, Geneva: World Health Organization; 2005.

[80]

Xue CC, Zhang AL, Lin V, Da Costa C, Story DF. Complementary and alternative medicine use in Australia: a national population-based survey. J Altern Complement Med 2007; 13(6):643-650. doi:10.1089/ acm.2006.6355, PMID:17718647.

[81]

Zhang Z, Li R, Chen Y, Yang H, Fitzgerald M, Wang Q, et al. Integration of traditional, complementary, and alternative medicine with modern biomedicine: the scientization, evidence, and challenges for integration of traditional Chinese medicine. Acupunct Herb Med 2024; 4(1):68-78. doi:10.1097/HM9.0000000000000089.

[82]

Sutherland P, Moodley R, Chevannes P. Caribbean healing traditions: Implications for health and mental health. 1st ed. New York: Routledge; 2013:doi:10.4324/9780203844502.

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