Synthesis of 1-aryl-2-propanones

Abstract

A new convenient synthesis of a series of 1-aryl-2-propanones using aromatic amines as precursors, via diazo-reaction and improved Meerwein arylation reaction under mild conditions, was achieved. In addition, 1-[3,5-bis(trifluoromethyl)phenyl]-2-propanone is a new compound among the synthesized compounds. This approach is an efficient synthetic method for the aryl-propanones with different substituting groups.

Keywords

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