Synthesis and characterization of 5-bromo-3--butyl-6-methyluracil

REN Huixue; YANG Yanzhao; LIN Jimao; QI Yinshan; ZHANG Yeqing

doi:10.1007/s11458-008-0029-9

Front. Chem. China ›› 2008, Vol. 3 ›› Issue (2) :152 -156. DOI: 10.1007/s11458-008-0029-9

Synthesis and characterization of 5-bromo-3--butyl-6-methyluracil

REN Huixue¹, YANG Yanzhao², LIN Jimao², QI Yinshan³, ZHANG Yeqing³

Author information +

History +

PDF (104KB)

Abstract

A new synthetic method for 5-bromo-3-sec-butyl-6-methyluracil (Bromacil) using 2-bromobutane and urea as starting materials is described. The synthesis involved condensation, cyclization and bromination with a total yield of 60%. The structure of Bromacil was determined by ¹H NMR, ¹³ C NMR and IR spectroscopy.

Keywords

Bromacil / condensation / cyclization, bromination

Cite this article

Download citation ▾

REN Huixue, YANG Yanzhao, LIN Jimao, QI Yinshan, ZHANG Yeqing. Synthesis and characterization of 5-bromo-3--butyl-6-methyluracil. Front. Chem. China, 2008, 3(2): 152-156 DOI:10.1007/s11458-008-0029-9