Synthesis and characterization of 5-bromo-3--butyl-6-methyluracil

Front. Chem. China ›› 2008, Vol. 3 ›› Issue (2) : 152 -156.

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Front. Chem. China ›› 2008, Vol. 3 ›› Issue (2) : 152 -156. DOI: 10.1007/s11458-008-0029-9

Synthesis and characterization of 5-bromo-3--butyl-6-methyluracil

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Abstract

A new synthetic method for 5-bromo-3-sec-butyl-6-methyluracil (Bromacil) using 2-bromobutane and urea as starting materials is described. The synthesis involved condensation, cyclization and bromination with a total yield of 60%. The structure of Bromacil was determined by 1H NMR, 13 C NMR and IR spectroscopy.

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Bromacil / condensation / cyclization, bromination

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null. Synthesis and characterization of 5-bromo-3--butyl-6-methyluracil. Front. Chem. China, 2008, 3(2): 152-156 DOI:10.1007/s11458-008-0029-9

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