Shape-memory and biocompatibility properties of segmented polyurethanes based on poly(L-lactide)

PING Peng1, WANG Wenshou1, ZHANG Peibiao2, CHEN Xuesi2, JING Xiabin2

Front. Chem. China ›› 2007, Vol. 2 ›› Issue (4) : 331-336.

PDF(379 KB)
PDF(379 KB)
Front. Chem. China ›› 2007, Vol. 2 ›› Issue (4) : 331-336. DOI: 10.1007/s11458-007-0063-z

Shape-memory and biocompatibility properties of segmented polyurethanes based on poly(L-lactide)

  • PING Peng1, WANG Wenshou1, ZHANG Peibiao2, CHEN Xuesi2, JING Xiabin2
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Abstract

A series of segmented poly(L-lactide)-polyurethanes (PLA-PUs) were synthesized by a twostep method, with oligo-poly(L-lactide) (PLA) as the soft segments and the reaction product of 2,4-toluene diisocyanate (TDI) and ethylene glycol (EG) as the hard segments. The shape-memory properties and biocompatibility of PLA-PUs were examined. The 50% compressed PLA-PUs could recover almost 100% to their original shape within 10! from the lowest recovery temperature (22!-37!). In the recovery process the PLA-PU showed a maximum contracting stress in the range of 1.5-4 MPa. Cell incubation experiments show that PLA-PU has biocompatibility comparable to that of pure PLA. Therefore, this kind of polyurethane can be used for implanted medical devices with shape memory requirements.

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PING Peng, WANG Wenshou, ZHANG Peibiao, CHEN Xuesi, JING Xiabin. Shape-memory and biocompatibility properties of segmented polyurethanes based on poly(L-lactide). Front. Chem. China, 2007, 2(4): 331‒336 https://doi.org/10.1007/s11458-007-0063-z
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