Synthesis and Fungicidal Activity of 1,3,4-Oxadiazole Substituted Acylthioureas

doi:10.1007/s11458-005-0020-7

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Front. Chem. China ›› 2006, Vol. 1 ›› Issue (1) : 112-114. DOI: 10.1007/s11458-005-0020-7

Synthesis and Fungicidal Activity of 1,3,4-Oxadiazole Substituted Acylthioureas

Wang Fenhua, Qin Zhanglan, Huang Qin

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Abstract

A series of N 2-(5-aryl-1,3,4-oxadiazole-2-yl) actylthioureas have been synthesized from p-chlorophenoxyacetic acid, and then substituted 2-amino-5-aryl-1,3,4-oxadiazoles reacting with acylthiocyanoester, which are derived from the second step, are used. Their structures are confirmed by Infrared, ¹H nuclear magnetic resonance, and elementary analysis. From biological testing, it is found that some of these compounds have good fungicidal activity.

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Wang Fenhua, Qin Zhanglan, Huang Qin. Synthesis and Fungicidal Activity of 1,3,4-Oxadiazole Substituted Acylthioureas. Front. Chem. China, 2006, 1(1): 112‒114 https://doi.org/10.1007/s11458-005-0020-7