Frontiers of Agriculture in China >
Protective effects of selenium and vitamin E on rats consuming maize naturally contaminated with mycotoxins
Received date: 16 Sep 2008
Accepted date: 09 Oct 2008
Published date: 05 Mar 2009
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Protective effects of antioxidant additives of selenium and vitamin E on rats that consumed maize naturally contaminated with mycotoxins were explored in this paper. Thirty-two Wistar female rats were randomly divided into four groups. The control group was given the basic diet with normal maize. The contaminated maize group was given the diet in which normal maize was replaced by mycotoxin-contaminated maize. The selenium group and vitamin E group were respectively fed mycotoxin-contaminated diet supplemented with 0.4 mg•middot;kg-1 selenium from yeast or 100 mg•middot;kg-1 vitamin E. The trial lasted for 4 weeks. Compared with the control group, antioxidative status was decreased significantly in the contaminated maize group. However, the status in the selenium group and vitamin E group was increased significantly compared with the contaminated maize group. The activities of enzymes related with liver function were significantly higher in the contaminated maize group than those in the control group, whereas they were significantly lower in the selenium group and/or the vitamin E group compared to the contaminated maize group. It is concluded that selenium and vitamin E were able to alleviate oxidative stress and liver function damage due to the consumption of maize naturally contaminated with mycotoxins.
Key words: selenium; vitamin E; mycotoxin-contaminated maize; rats
Jie YU , Daiwen CHEN , Bing YU . Protective effects of selenium and vitamin E on rats consuming maize naturally contaminated with mycotoxins[J]. Frontiers of Agriculture in China, 2009 , 3(1) : 95 -99 . DOI: 10.1007/s11703-009-0015-0
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