Effects of aflatoxin-detoxifizyme on growth performance and liver biochemical indices of broilers fed with aflatoxin B₁

Abstract

Aflatoxin-detoxifizyme (ADTZ) was evaluated for its ability to reduce the deleterious effects of aflatoxin B₁ (AFB₁) in broiler diets. A total of 624 one-day-old AA broilers were randomly divided into 3 treatment groups with 8 replicates each. The control, AFB₁ and ADTZ treatments were fed with basal diet, basal diet+ 0.1 mg/kg AFB₁ and basal diet+ 0.1 mg/kg AFB₁ + 0.3% ADTZ, respectively. The trials lasted 42 days. The results showed that: (1) AFB₁ diminished the growth performance of broilers significantly (P<0.01). (2) The AFB₁ supplement caused significant alteration of related liver enzyme activities and significantly decreased the body’s antioxidant capacity. (3) Related parameters were returned to normal levels by a 0.3% ADTZ addition to the AFB₁-contaminated diet. All the results in the trials indicate that ADTZ has the ability to detoxify AFB₁ and recover the negative effects of AFB₁.

Keywords

aflatoxin-detoxifizyme (ADTZ) / aflatoxin B₁(AFB₁) / broilers / growth performance / liver biochemical indices

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