Emerging therapies of hemangioblastomas

Chaitanya Sanghadia , Melanie E. Martinez , Marisa McNulty , Eric Russ , Maxwell Woolridge , Dat Thanh Cao , Marko Micunovic , Jeffery Roberts , Juan Perez , Brandon Lucke-Wold

Exploration of Neuroscience ›› 2023, Vol. 2 ›› Issue (6) : 318 -330.

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Exploration of Neuroscience ›› 2023, Vol. 2 ›› Issue (6) :318 -330. DOI: 10.37349/en.2023.00031
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Emerging therapies of hemangioblastomas
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Abstract

Hemangioblastoma are benign, vascularized cranial tumors caused by autosomal dominant inherited von Hippel-Lindau disease or can appear sporadically. This review will investigate current and emerging treatments for cerebral tumors. It will focus on the current and, more importantly, developing hemangioblastoma treatments. Surgical resectioning and radiotherapy are effective treatment options for cerebral tumors, whereas chemotherapies are not commonly used due to their limited ability to penetrate the blood-brain barrier. Recent chemotherapies have shown promise, but further research is needed to determine the efficacy as a treatment for hemangioblastomas. New advances in brachytherapy and immunotherapy are considered promising treatment options for hemangioblastoma. This review aims to offer valuable insights into the latest developments in hemangioblastoma treatments.

Keywords

Hemangioblastoma / cerebral tumor / von Hippel-Lindau / chemotherapy / radiotherapy / brachytherapy / immunotherapy

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Chaitanya Sanghadia, Melanie E. Martinez, Marisa McNulty, Eric Russ, Maxwell Woolridge, Dat Thanh Cao, Marko Micunovic, Jeffery Roberts, Juan Perez, Brandon Lucke-Wold. Emerging therapies of hemangioblastomas. Exploration of Neuroscience, 2023, 2 (6) : 318-330 DOI:10.37349/en.2023.00031

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