Estimation of the allelic status of apolipoprotein E4 isoforms with fully automated LUMIPULSE® assays

Tatsushi Yuri , Rosina Degrieck , Dagmara Minczakiewicz , Hideo Sato , Jo Kamada , Takuya Nakazawa , Ina Vandenbroucke , Katsumi Aoyagi , Hisashi Nojima

Exploration of Neuroscience ›› 2023, Vol. 2 ›› Issue (5) : 238 -244.

PDF (2384KB)
Exploration of Neuroscience ›› 2023, Vol. 2 ›› Issue (5) :238 -244. DOI: 10.37349/en.2023.00024
research-article
Estimation of the allelic status of apolipoprotein E4 isoforms with fully automated LUMIPULSE® assays
Author information +
History +
PDF (2384KB)

Keywords

Apolipoprotein E4 / Alzheimer’s disease / disease modifying therapy / chemiluminescent enzyme immunoassay

Cite this article

Download citation ▾
Tatsushi Yuri, Rosina Degrieck, Dagmara Minczakiewicz, Hideo Sato, Jo Kamada, Takuya Nakazawa, Ina Vandenbroucke, Katsumi Aoyagi, Hisashi Nojima. Estimation of the allelic status of apolipoprotein E4 isoforms with fully automated LUMIPULSE® assays. Exploration of Neuroscience, 2023, 2 (5) : 238-244 DOI:10.37349/en.2023.00024

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Liu CC,Kanekiyo T,Xu H,Bu G.Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.Nat Rev Neurol.2013;9:106-18.

[2]

Corder EH,Saunders AM,Strittmatter WJ,Schmechel DE,Gaskell PC,Small GW,et al.Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families.Science.1993;261:921-3.

[3]

Farrer LA,Cupples LA,Haines JL,Hyman B,Kukull WA,Mayeux R,et al.Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium.JAMA.1997;278:1349-56.

[4]

Verghese PB,Castellano JM,Holtzman DM.Apolipoprotein E in Alzheimer’s disease and other neurological disorders.Lancet Neurol.2011;10:241-52.

[5]

Budd Haeberlein S,Aisen PS,Barkhof F,Chalkias S,Chen T,Cohen S,et al.Two randomized phase 3 studies of aducanumab in early Alzheimer’s disease.J Prev Alzheimers Dis.2022;9:197-210.

[6]

van Dyck CH,Swanson CJ,Aisen P,Bateman RJ,Chen C,Gee M,et al.Lecanemab in early Alzheimer’s disease.N Engl J Med.2023;388:9-21.

[7]

Cummings J,Rabinovici GD,Atri A,Aisen P,Apostolova LG,Hendrix S,et al.Aducanumab: appropriate use recommendations update.J Prev Alzheimers Dis.2022;9:221-30.

[8]

Cummings J,Apostolova L,Rabinovici GD,Atri A,Aisen P,Greenberg S,et al.Lecanemab: appropriate use recommendations.J Prev Alzheimers Dis.2023;10:362-77.

[9]

Filippi M,Cecchetti G,Spinelli EG,Vezzulli P,Falini A,Agosta F.Amyloid-related imaging abnormalities and β-amyloid-targeting antibodies: a systematic review.JAMA Neurol.2022;79:291-304.

[10]

Siest G,Pillot T,Régis-Bailly A,Leininger-Muller B,Steinmetz J,Galteau MM,et al.Apolipoprotein E: an important gene and protein to follow in laboratory medicine.Clin Chem.1995;41:1068-86.

[11]

Calero O,Hortigüela R,Bullido MJ,Calero M.Apolipoprotein E genotyping method by real time PCR, a fast and cost-effective alternative to the TaqMan® and FRET assays.J Neurosci Methods.2009;183:238-40.

[12]

Zhong L,Xie YZ,Cao TT,Wang Z,Wang T,Li X,et al.A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism.Mol Neurodegener.2016;11:2.

[13]

Dupuy AM,Badiou S,Ritchie K,Mas E,Descomps B,Cristol JP,et al.Discrepancies between apolipoprotein E phenotyping and genotyping in the elderly.Clin Chem Lab Med.2001;39:405-13.

[14]

Kataoka S,Paidi M,Howard BV.Simplified isoelectric focusing/immunoblotting determination of apoprotein E phenotype.Clin Chem.1994;40:11-3.

[15]

Uchida Y,Ito S,Nukina N.Sandwich ELISA for the measurement of Apo-E4 levels in serum and the estimation of the allelic status of Apo-E4 isoforms.J Clin Lab Anal.2000;14:260-4.

[16]

Niederkofler EE,Tubbs KA,Kiernan UA,Nedelkov D,Nelson RW.Novel mass spectrometric immunoassays for the rapid structural characterization of plasma apolipoproteins.J Lipid Res.2003;44:630-9.

[17]

Badrnya S,Doherty T,Richardson C,McConnell RI,Lamont JV,Veitinger M,et al.Development of a new biochip array for APOE4 classification from plasma samples using immunoassay-based methods.Clin Chem Lab Med.2018;56:796-802.

[18]

Ehara H,Yamamoto-Honda R,Kitazato H,Takahashi Y,Kawazu S,Akanuma Y,et al.ApoE isoforms, treatment of diabetes and the risk of coronary heart disease.World J Diabetes.2012;3:54-9.

[19]

Stavljenic-Rukavina A,Sertic J,Salzer B,Dumic M,Radica A,Fumic K,et al.Apolipoprotein E phenotypes and genotypes as determined by polymerase chain reaction using allele-specific oligonucleotide probes and the amplification refractory mutation system in children with insulin-dependent diabetes mellitus.Clin Chim Acta.1993;216:191-8.

[20]

Hixson JE,Vernier DT.Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.J Lipid Res.1990;31:545-8.

[21]

Belloy ME,Napolioni V,Greicius MD.A quarter century of APOE and Alzheimer’s disease: progress to date and the path forward.Neuron.2019;101:820-38.

[22]

Husain MA,Laurent B,Plourde M.APOE and Alzheimer’s disease: from lipid transport to physiopathology and therapeutics.Front Neurosci.2021;15:630502.

[23]

Iwatsubo T,Iwata A,Suzuki K,Ihara R,Arai H,Ishii K,et al.Japanese Alzheimer’s Disease Neuroimaging InitiativeSun CK,Beckett LA,Petersen RC,Weiner MW,Aisen PS,Donohue MCAlzheimer’s Disease Neuroimaging InitiativeJapanese and North American Alzheimer’s disease neuroimaging initiative studies: harmonization for international trials.Alzheimers Dement.2018;14:1077-87.

[24]

Veiga S,Rodríguez-Martín A,Garcia-Ribas G,Arribas I,Menacho-Román M,Calero M.Validation of a novel and accurate ApoE4 assay for automated chemistry analyzers.Sci Rep.2020;10:2138.

[25]

Palmqvist S,Stomrud E,Cullen N,Janelidze S,Manuilova E,Jethwa A,et al.An accurate fully automated panel of plasma biomarkers for Alzheimer’s disease.Alzheimers Dement.2023;19:1204-15.

[26]

Srivastava RAK.Regulation of the apolipoprotein E by dietary lipids occurs by transcriptional and post-transcriptional mechanisms.Mol Cell Biochem.1996;155:153-62.

[27]

Janelidze S,Bali D,Ashton NJ,Barthélemy NR,Vanbrabant J,Stoops E,et al.Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease.Brain.2023;146:1592-601.

[28]

Nojima H,Ito S,Kushida A,Abe A,Motsuchi W,Verbel D,et al.Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system.Ann Clin Transl Neurol.2022;9:1898-909.

[29]

Musso G,Cosma C,Zaninotto M,Gabelli C,Basso D,Plebani M.Pre-analytical variability of the Lumipulse immunoassay for plasma biomarkers of Alzheimer’s disease.Clin Chem Lab Med.2023;61:e53-6.

PDF (2384KB)

0

Accesses

0

Citation

Detail

Sections
Recommended

/