From gains to liver pain: when exercise training goes too far

Abstract

A recent study from Liu et al. described the role of skeletal muscle-derived extracellular vesicles in promoting liver fibrosis as an outcome of chronic overtraining in mice. Here, we highlight this work and discuss its implications within the fields of exercise physiology and inter-organ communication.

Keywords

Extracellular vesicles / overtraining / liver fibrosis / skeletal muscle / inter-organ communication / exercise physiology

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