Sustained release of cytokines from migrasomes
Yan Zhen , Harald Stenmark
Extracellular Vesicles and Circulating Nucleic Acids ›› 2025, Vol. 6 ›› Issue (1) : 171 -5.
Sustained release of cytokines from migrasomes
Cytokines are released by cells in response to infections and tissue damage. A recent paper by Jiao et al. demonstrates that circulating monocytes release the cytokines tumor necrosis factor and Interleukin-6 encapsulated in large extracellular vesicles called migrasomes, from which the cytokines are secreted locally in a sustained fashion.
Cytokine / extracellular vesicles / inflammation / interleukin / migrasome / monocyte
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