Sustained release of cytokines from migrasomes

Yan Zhen , Harald Stenmark

Extracellular Vesicles and Circulating Nucleic Acids ›› 2025, Vol. 6 ›› Issue (1) : 171 -5.

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Extracellular Vesicles and Circulating Nucleic Acids ›› 2025, Vol. 6 ›› Issue (1) :171 -5. DOI: 10.20517/evcna.2025.15
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Sustained release of cytokines from migrasomes

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Abstract

Cytokines are released by cells in response to infections and tissue damage. A recent paper by Jiao et al. demonstrates that circulating monocytes release the cytokines tumor necrosis factor and Interleukin-6 encapsulated in large extracellular vesicles called migrasomes, from which the cytokines are secreted locally in a sustained fashion.

Keywords

Cytokine / extracellular vesicles / inflammation / interleukin / migrasome / monocyte

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Yan Zhen, Harald Stenmark. Sustained release of cytokines from migrasomes. Extracellular Vesicles and Circulating Nucleic Acids, 2025, 6(1): 171-5 DOI:10.20517/evcna.2025.15

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