Inhalable exosomes to target cardiac repair
Ajit Magadum
Extracellular Vesicles and Circulating Nucleic Acids ›› 2025, Vol. 6 ›› Issue (1) : 180 -2.
Inhalable exosomes to target cardiac repair
A recent study introduces Stem Cell-derived Exosome Nebulization Therapy (SCENT), a novel, non-invasive strategy that delivers lung spheroid cell-derived exosomes via inhalation to promote cardiac repair after myocardial infarction. This approach improves cardiac function, reduces injury, and demonstrates translational potential in both small and large animal models, offering a promising avenue for cell-free, inhalable regenerative therapies.
Inhalation / exosomes / cardiovascular disease / CD36 / non-invasive delivery
| [1] |
|
| [2] |
|
| [3] |
|
| [4] |
|
| [5] |
de Abreu RC, Fernandes H, da Costa Martins PA, Sahoo S, Emanueli C, Ferreira L. Native and bioengineered extracellular vesicles for cardiovascular therapeutics.Nat Rev Cardiol2020;17:685-97 PMCID:PMC7874903 |
/
| 〈 |
|
〉 |