Carbon sequestration pathways in microorganisms: Advances, strategies, and applications

Abstract

In recent years, industrial activities have significantly increased atmospheric CO₂ levels, exacerbating global warming. Carbon reduction involves implementing measures to minimize CO₂ emissions from human activities and achieve a balance between carbon absorption and emissions. Therefore, effective reduction of CO₂ emissions is crucial. Conventional physical and chemical methods for CO₂ fixation frequently cause secondary environmental pollution. As a result, utilizing microorganisms for CO₂ fixation has gained considerable interest. This review provides an overview of the natural pathways for microbial CO₂ fixation, recent advancements in artificial CO₂ fixation, and strategies for enhancing the efficiency of microbial CO₂ fixation. We also discuss the conversion of CO₂ into diverse metabolic products and high-value chemicals. By identifying efficient carbon fixation pathways for microorganisms, this review aims to lay the foundation for the biological production of high-value chemicals using CO₂ as a raw material.

Keywords

CO₂ fixation / Metabolic pathway / Value-added products / Natural carbon fixation pathways / Artificial carbon sequestration pathways

Declaration of Competing Interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence thework reported in this paper.

CRediT Authorship Contribution Statement

Shupeng Ruan: Writing - review & editing, Writing - original draft, Investigation. Yuchen Jiang: Writing - original draft. Aoxue Wang: Writing - original draft. Xinying Zhang: Writing - original draft. Ying Lin: Writing - review & editing, Supervision, Resources, Methodology. Shuli Liang: Writing - review & editing, Visualization, Supervision, Methodology, Investigation.

Acknowledgements

This work was supported by the National Key Research and Development Program (2021YFC2104000), the National Natural Science Foundation of China (32272276), and the Fundamental Research Funds for the Central Universities.

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