Current concepts on the intervention for adhesive capsulitis

Abeer Alomari , Philip Peng

Exploration of Musculoskeletal Diseases ›› 2025, Vol. 3 ›› Issue (1) : 1007110

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Exploration of Musculoskeletal Diseases ›› 2025, Vol. 3 ›› Issue (1) :1007110 DOI: 10.37349/emd.2025.1007110
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Current concepts on the intervention for adhesive capsulitis
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Abstract

Adhesive capsulitis, or frozen shoulder, is characterized by pain and progressive restriction of both active and passive shoulder range of motion. The pathophysiology involves an initial inflammatory phase with elevated cytokines, followed by pathological fibrosis, capsular thickening, and contracture involving both intra- and extra-articular structures, including the coracohumeral ligament and rotator cuff interval. Diagnosis is primarily clinical. The traditional three-stage model, freezing, frozen, and thawing, has been challenged by recent evidence showing that spontaneous recovery is uncommon and that many patients do not fully regain shoulder function without active treatment. This paradigm change emphasizes the necessity of early and focused interventions to maximize functional recovery. While physiotherapy remains the mainstay of management, interventional procedures have gained prominence for their ability to reduce pain and facilitate rehabilitation. Interventional options include intra-articular corticosteroid injections, hydrodilatation, and suprascapular nerve blocks. This narrative review summarizes current evidence on interventional procedures for adhesive capsulitis, highlighting their mechanisms, techniques, and comparative efficacy.

Keywords

adhesive capsulitis / frozen shoulder / rotator cuff interval / injection

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Abeer Alomari, Philip Peng. Current concepts on the intervention for adhesive capsulitis. Exploration of Musculoskeletal Diseases, 2025, 3 (1) : 1007110 DOI:10.37349/emd.2025.1007110

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References

[1]

Neviaser JS. Adhesive capsulitis of the shoulder: a study of the pathological findings in periarthritis of the shoulder. J Bone Joint Surg. 1945; 27: 211-22.

[2]

Huang Y, Fann C, Chiu Y, Yen M, Chen L, Chen H, et al. Association of diabetes mellitus with the risk of developing adhesive capsulitis of the shoulder: a longitudinal population-based followup study. Arthritis Care Res (Hoboken). 2013; 65: 1197-202.

[3]

Sarasua SM, Floyd S, Bridges WC, Pill SG. The epidemiology and etiology of adhesive capsulitis in the U.S. Medicare population. BMC Musculoskelet Disord. 2021; 22: 828.

[4]

Feeley SM, Larson ES, Diduch DR. Adhesive Capsulitis: Current Concepts. Ann Sports Med Res. 2017; 4: 1124.

[5]

Ewald A. Adhesive capsulitis: a review. Am Fam Physician. 2011; 83: 417-22.

[6]

Hollmann L, Halaki M, Kamper SJ, Haber M, Ginn KA. Does muscle guarding play a role in range of motion loss in patients with frozen shoulder? Musculoskelet Sci Pract. 2018; 37: 64-8.

[7]

Brindisino F, Rizzo V, Dejaco B, Andriesse A, Verardo A, Turolla A. Association between pain, stiffness, mood, catastrophizing, and perceived social support, in subjects with frozen shoulder: A cross-sectional study. Shoulder Elbow. 2025;17585732251338652.

[8]

de Winter AF, Jans MP, Scholten RJ, Devillé W, Schaardenburg Dv, Bouter LM. Diagnostic classification of shoulder disorders: interobserver agreement and determinants of disagreement. Ann Rheum Dis. 1999; 58: 272-7.

[9]

Walmsley S, Rivett DA, Osmotherly PG. Adhesive capsulitis: establishing consensus on clinical identifiers for stage 1 using the DELPHI technique. Phys Ther. 2009; 89: 906-17.

[10]

Walmsley S, Osmotherly PG, Rivett DA. Clinical identifiers for early-stage primary/idiopathic adhesive capsulitis: are we seeing the real picture? Phys Ther. 2014; 94: 968-76.

[11]

Picasso R, Pistoia F, Zaottini F, Marcenaro G, Miguel-Pérez M, Tagliafico AS, et al. Adhesive Capsulitis of the Shoulder: Current Concepts on the Diagnostic Work-Up and Evidence-Based Protocol for Radiological Evaluation. Diagnostics (Basel). 2023; 13: 3410.

[12]

Reeves B. The natural history of the frozen shoulder syndrome. Scand J Rheumatol. 1975; 4: 193-6.

[13]

Clarke GR, Willis LA, Fish WW, Nichols PJ. Preliminary studies in measuring range of motion in normal and painful stiff shoulders. Rheumatol Rehabil. 1975; 14: 39-46.

[14]

Shaffer B, Tibone JE, Kerlan RK. Frozen shoulder. A long-term follow-up. J Bone Joint Surg Am. 1992; 74: 738-46.

[15]

Wong CK, Levine WN, Deo K, Kesting RS, Mercer EA, Schram GA, et al. Natural history of frozen shoulder: fact or fiction? A systematic review. Physiotherapy. 2017; 103: 40-7.

[16]

Kraal T, Lübbers J, van den Bekerom MPJ, Alessie J, van Kooyk Y, Eygendaal D, et al. The puzzling pathophysiology of frozen shoulders - a scoping review. J Exp Orthop. 2020; 7: 91.

[17]

Le HV, Lee SJ, Nazarian A, Rodriguez EK. Adhesive capsulitis of the shoulder: review of pathophysiology and current clinical treatments. Shoulder Elbow. 2017; 9: 75-84.

[18]

Tamai K, Hamada J, Nagase Y, Morishige M, Naito M, Asai H, et al. Frozen shoulder. An overview of pathology and biology with hopes to novel drug therapies. Mod Rheumatol. 2024; 34: 439-43.

[19]

Cho C, Bae K, Kim D. Treatment Strategy for Frozen Shoulder. Clin Orthop Surg. 2019; 11: 249-57.

[20]

Cho JH. Updates on the treatment of adhesive capsulitis with hydraulic distension. Yeungnam Univ J Med. 2021; 38: 19-26.

[21]

Poku D, Hassan R, Migliorini F, Maffulli N. Efficacy of hydrodilatation in frozen shoulder: a systematic review and meta-analysis. Br Med Bull. 2023; 147: 121-47.

[22]

Liang C, Cheng H, Lee Y, Liao CD, Huang S. Corticosteroid Injection Methods for Frozen Shoulder: A Network Meta-analysis. Arch Phys Med Rehabil. 2024; 105: 750-9.

[23]

Challoumas D, Biddle M, McLean M, Millar NL. Comparison of Treatments for Frozen Shoulder: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020; 3: e2029581.

[24]

Pimenta M, Vassalou EE, Klontzas ME, Dimitri-Pinheiro S, Ramos I, Karantanas AH. Ultrasound-guided hydrodilatation for adhesive capsulitis: capsule-preserving versus capsule-rupturing technique. Skeletal Radiol. 2024; 53: 253-61.

[25]

Peng PWH, Cheng P. Ultrasound-guided interventional procedures in pain medicine: a review of anatomy, sonoanatomy, and procedures. Part III: shoulder. Reg Anesth Pain Med. 2011; 36: 592-605.

[26]

Arrambide-Garza FJ, Guerrero-Zertuche JT, Alvarez-Villalobos NA, Quiroga-Garza A, Espinosa-Uribe A, Vilchez-Cavazos F, et al. Rotator Interval vs Posterior Approach Ultrasound-guided Corticosteroid Injections in Primary Frozen Shoulder: A Meta-analysis of Randomized Controlled Trials. Arch Phys Med Rehabil. 2024; 105: 760-9.

[27]

Kozlowski BJ, Tran J, Peng PWH, Agur AMR, Mittal N. Comparison of the spread pattern of medial-to-lateral and lateral-to-medial rotator interval injections: A cadaveric study. Interv Pain Med. 2022; 1: 100164.

[28]

Mittal N, Salonen D, Peng P. Assessing injectate spread in ultrasound-guided capsular hydro dilatation for adhesive capsulitis: A comparative MRI study of anterior rotator interval vs. posterior glenohumeral joint approaches. Interv Pain Med. 2025; 4: 100557.

[29]

Chan C, Peng PWH. Suprascapular nerve block: a narrative review. Reg Anesth Pain Med. 2011; 36: 358-73.

[30]

Tran J, Peng PWH, Agur AMR. Anatomical study of the innervation of glenohumeral and acromioclavicular joint capsules: implications for image-guided intervention. Reg Anesth Pain Med. 2019;rapm-2018-100152.

[31]

Laumonerie P, Dalmas Y, Tibbo ME, Robert S, Faruch M, Chaynes P, et al. Sensory innervation of the human shoulder joint: the three bridges to break. J Shoulder Elbow Surg. 2020; 29: e499-507.

[32]

Bennett J, Patel N, Nantha-Kumar N, Phillips V, Nayar SK, Kang N. Assessing the effectiveness of suprascapular nerve block in the treatment of frozen shoulder. Bone Joint J. 2025; 107-B: 19-26.

[33]

Jadon A, Sanyal S, Pavan S, Bakshi A, Bharadwaj A, Singh AP. Suprascapular Nerve Block (SSNB) improves the outcome in exercise based management of Primary Adhesive Capsulitis (PAC): A prospective randomized comparative study. J Anaesthesiol Clin Pharmacol. 2023; 39: 195-200.

[34]

Kumar S, Khuba S, Gautam S, Agarwal A, Chatterjee A, Goyal N, et al. Comparative efficacy of ultrasound-guided combined suprascapular and axillary nerve block with suprascapular nerve block alone in patients with frozen shoulder: A prospective, double-blinded randomized, single-centre trial. Interv Pain Med. 2023; 2: 100265.

[35]

Kelley MJ, Shaffer MA, Kuhn JE, Michener LA, Seitz AL, Uhl TL, et al. Shoulder pain and mobility deficits: adhesive capsulitis. J Orthop Sports Phys Ther. 2013; 43: A1-31.

[36]

Peng P, Finlayson R, Lee SH, Bhatia A, editors. Ultrasound for Interventional Pain Management. Cham: Springer; 2020.

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