Ferroptosis inhibition: New insights for the treatment of acute lung injury

Xuhan Chen; Jinhe Guo

doi:10.36922/EJMO025090043

Eurasian Journal of Medicine and Oncology ›› 2025, Vol. 9 ›› Issue (3) :300 -301. DOI: 10.36922/EJMO025090043

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Ferroptosis inhibition: New insights for the treatment of acute lung injury

Xuhan Chen
, Jinhe Guo ^*

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Xuhan Chen, Jinhe Guo. Ferroptosis inhibition: New insights for the treatment of acute lung injury. Eurasian Journal of Medicine and Oncology, 2025, 9(3): 300-301 DOI:10.36922/EJMO025090043

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The Science & Technology Development Fund of Tianjin Education Commission for Higher Education (2023KJ131).

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The authors declare no competing interests.

References

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[1]	Zhao L, Ge G, Li J, Han X. The improvement effect of osthole on lung injury in rats with mycoplasma pneumoniae pneumonia through the Nrf2-Gpx4 ferroptosis pathway. ZCY. 2023; 45(1):48-54.

[2]	Zhang H, Zhang Y, Fu J, et al. Research progress on the induction of ferroptosis in tumor cells by active ingredients of traditional Chinese medicine. Chin J Exp Tradit Med Formul. 2024; 30(9):245-253. doi: 10.13422/j.cnki.syfjx.20232121

[3]	Chen Z, Tang H, Gan S, et al. Ferroptosis mediates airway epithelial E-cadherin dysfunction in LPS-induced acute lung injury. Pulm Pharmacol Ther. 2024; 84:102284. doi: 10.1016/j.pupt.2023.102284

[4]	Zhang J, Zheng Y, Wang Y, et al. YAP1 alleviates sepsis-induced acute lung injury via inhibiting ferritinophagy-mediated ferroptosis. Front Immunol. 2022; 13:884362. doi: 10.3389/fimmu.2022.884362

[5]	Wang Y, Chen D, Xie H, et al. AUF1 protects against ferroptosis to alleviate sepsis-induced acute lung injury by regulating NRF2 and ATF3. Cell Mol Life Sc. 2022; 79(5):228. doi: 10.1007/s00018-022-04248-8

[6]	Li C, Wang H, He Q, Guo X, Jiang T, Guo Y. Study on the effect and mechanism of quercetin in inhibiting the proliferation of A549 cells by inducing ferroptosis. Chin Herb Med. 2022; 53(22):7112-7120.

[7]	Li J, Li Z, Li X, Liang Q, Liao C, Li F. Exploration of the protective effect of Ganlu Qingwen formula on rats with acute lung injury based on the Nrf2/GPX4 ferroptosis pathway. ZCY. 2024; 47(2):596-600.

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Sun Z, Wang L, Suo H, Li H, Chen Q. Exploration of the protective effect of jiawei taoren chengqi decoction on rats with ventilator-associated lung injury based on the Nrf2/ GPX4 ferroptosis pathway. Tradit Chin Drug Res Clin Pharmacol. 2024; 35(9):1281-1288. doi: 10.19378/j.issn.1003-9783.2024.09.001

[9]	Zhao L, Ge G, Li J, Han X. The improvement effect of osthole on lung injury in rats with mycoplasma pneumoniae pneumonia through the Nrf2-Gpx4 ferroptosis pathway. ZCY. 2023; 45(1):48-54.