Importance of probiotics and prebiotics and their mechanism of immune action against COVID-19: a narrative review

Norma Angélica Santiesteban-López , Yesbek Rocío Morales Paredes , Teresa Gladys Cerón Carrillo , Juan Chávez Medina

Exploration of Foods and Foodomics ›› 2025, Vol. 3 ›› Issue (1) : 101081

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Exploration of Foods and Foodomics ›› 2025, Vol. 3 ›› Issue (1) :101081 DOI: 10.37349/eff.2025.101081
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Importance of probiotics and prebiotics and their mechanism of immune action against COVID-19: a narrative review
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Abstract

The study investigated the role of probiotics and prebiotics in treating COVID-19. It focuses on their mechanisms of action in modulating the immune system and mitigating the disease’s impact. The research focused on the significance of the gut-lung axis and the potential benefits of probiotics and prebiotics against COVID-19. The research identified several findings: probiotics have shown potential in reducing the severity of COVID-19 symptoms and improving patient outcomes. The gut microbiota plays a critical role in the body’s immune response to COVID-19, with probiotics aiding in restoring its balance. Both can modulate the immune system, reducing the inflammatory response associated with COVID-19. While there is evidence supporting the benefits of probiotics and prebiotics, limitations exist due to the lack of studies on their use to improve COVID-19 outcomes. The originality of the study is focused on the gut-lung axis and the review of probiotics and prebiotics as potential therapies for COVID-19. By analyzing recent literature, the research contributes to understanding the interactions between diet, gut health, and respiratory infections. It also shows the need for further studies to determine the efficacy of COVID-19, toward new directions for research in the emerging field.

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Probiotics / prebiotics / mechanisms of action / COVID-19 / immunological system

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Norma Angélica Santiesteban-López, Yesbek Rocío Morales Paredes, Teresa Gladys Cerón Carrillo, Juan Chávez Medina. Importance of probiotics and prebiotics and their mechanism of immune action against COVID-19: a narrative review. Exploration of Foods and Foodomics, 2025, 3 (1) : 101081 DOI:10.37349/eff.2025.101081

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