Association study of APOE, LPL and NOS3 polymorphisms with the risk of common cardio pathology in children and pregnant women
Andrey S Glotov , Elena S Vashukova , Maria D Kanaeva , Maria O Dvoeglazova , Maria M Danilova , Vladimir S Pakin , Ekaterina Yu Marochkina , Dina R Bicmullina , Maria A Glebova , Irina A Makhrova , Galina I Obraztsova , Oleg S Glotov , Marina S Zainulina , Tatyana E Ivashchenko , Vladislav S Baranov
Ecological Genetics ›› 2011, Vol. 9 ›› Issue (4) : 25 -34.
Association study of APOE, LPL and NOS3 polymorphisms with the risk of common cardio pathology in children and pregnant women
Polymorphisms of APOE (E2/E3/E4), LPL (1595C>G) and NOS3 (-786T>C) in groups of pregnant women with and without preeclampsia, in donors, in children with hypertension, children with obesity and metabolic syndrome, and in control children were studied by PCR /RF LP analysis. Statistically significant increase of T/C genotype frequency of NOS3 in pregnant women with preeclampsia as well as in women with physiological pregnancy compared to this one in nonpregnant women of donors group was assessed (56%, 59% and 37%, respectively, F<0.03).
Glotov A.S., Vashukova E.S., Kanaeva M.D., Dvoeglazova M.O., Danilova M.M., Pakin V.S., Marochkina E.Y., Bicmullina D.R., Glebova M.A., Makhrova I.A., Obraztsova G.I., Glotov O.S., Zainulina M.S., Ivashchenko T.E., Baranov V.S.
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