Modern technologies for the production of vaccines against avian infectious diseases

Abstract

Vaccination is one of the most effective and versatile ways to prevent infectious diseases. The development of modern technologies makes it possible to obtain vaccines with desired properties. The review presents data on different types of vaccines used for the prevention of infectious diseases of birds. The advantages and disadvantages of traditional attenuated and inactivated vaccines, as well as recombinant vaccines – vector, subunit, based on virus-like particles and DNA vaccines – are considered. Possibilities of bacterial, yeast, baculovirus and plant systems for the expression of heterologous genes for the production of recombinant vaccines are discussed.

Keywords

avian vaccination / live attenuated vaccine / inactivated vaccine / vector vaccine / recombinant vaccine / virus-like particles / adjuvants / transgenic organism-producer

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Funding

Санкт-Петербургский государственный университет, Санкт-ПетербургSaint Petersburg State University, Saint Petersburg, Russia(Грант СПбГУ ID: 75428571)