INTERACTION OF RECOMBINANT TATA-BINDING PROTEIN WITH MAMMALS GENES PROMOTER TATA
Ludmila K Savinkova , Irina A Drachkova , Michail P Ponomarenko , Marina V Lysova , Tatiana V Arshinova , Nikolay A Kolchanov
Ecological Genetics ›› 2007, Vol. 5 ›› Issue (2) : 44 -49.
INTERACTION OF RECOMBINANT TATA-BINDING PROTEIN WITH MAMMALS GENES PROMOTER TATA
Quantitative characteristics of interaction recombinant TATA-binding protein (TBP) with oligonucleotides identical to natural TATA-containing promoter region genes of mammals are received. In particular, new experimental data about the importance guanine in 8-th position of the TATA-element for affinity to TBP are received. The experimental data, testifying that raised maintenance G and С nucleotides in flanks of TATA-element does the contribution to affinity to TBP are received.
Savinkova L.K., Drachkova I.A., Ponomarenko M.P., Lysova M.V., Arshinova T.V., Kolchanov N.A.
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