Examination of the working environment genotoxic effects on the workers of a coal-fired power plant using the micronucleus test in blood lymphocytes
Vladislav I. Fedoseev , Danil D. Stepanov , Varvara I. Minina
Ecological Genetics ›› 2021, Vol. 19 ›› Issue (1) : 77 -88.
Examination of the working environment genotoxic effects on the workers of a coal-fired power plant using the micronucleus test in blood lymphocytes
BACKGROUND: The micronucleus test of peripheral blood lymphocytes provides a qualitative assessment of the state of the genome. A study was carried out aimed at studying the influence of factors of the working environment of coal-fired power plants on the state of the DNA of working data of enterprises.
MATERIALS AND METHODS: Using a micronucleus test with a cytochalasin block on human blood lymphocytes in vitro, 116 men were examined: 45 employees of the Novo-Kemerovo coal-fired power plant and 71 healthy residents of the Kemerovo region.
RESULTS: An increase in the frequency of occurrence of cells with micronuclei, bridges and protrusions in the blood lymphocytes of workers of a coal-fired power plant in comparison with healthy residents of the same area was found.
CONCLUSION: The data confirm the existing idea of the potential danger of combustion products for human health.
micronuclear testing / blood lymphocytes / thermal power plants / occupational groups / genotoxicity
Fedoseev V.I., Stepanov D.D., Minina V.I.
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