Overexpression of genes encoding asparagine-glutamine rich transcriptional factors causes nonsense suppression in Saccharomyces cerevisiae

Abstract

Previously, we have carried out a search for genes, whose overexpression causes nonsense suppression on the background of modified SUP35 variants expression in yeast Saccharomyces cerevisiae. Here we analyzed the influence of genes encoding N/Q-rich transcriptional factors on this process. We demonstrated that GLN3, MCM1, MOT3 and REB1 genes overexpression affects nonsense suppression in S. cerevisiae

Keywords

amyloid / nonsense suppression / prion / yeast / translation termination

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RIGHTS & PERMISSIONS

Nizhnikov A.A., Kondrashkina A.M., Antonets K.S., Galkin A.P.